Computational Models of Pharmacological and Immunological Treatment in Alzheimer’s Disease

Vassilis Cutsuridis, Ahmed Abdelhaim Moustafa

Research output: Chapter in Book/Report/Conference proceedingChapterResearchpeer-review


Alzheimer’s disease (AD) is a neurological disorder, mostly associated with cognitive decline in older age, although it can also happen in younger age (under 55 years old). The prevalence of AD increases as we get older, with at least a quarter of the population over 85 being diagnosed with the disease. The exact causes of AD and how it progresses over age are not known, but research has identified many factors, including behavioural, metabolic, genetic, and immunological ones. Beside memory decline, patients with AD also show language deficits, including difficulty remembering meaning of words and naming objects (Tippett & Farah, 1994) and word finding and comprehension (Ferris & Farlow, 2013). Patients with AD also exhibit impairment in executive processes in comparison to age matched healthy controls (Baudic, Barba, Thibaudet, Smagghe, Remy, & Traykov, 2006; Perry & Hodges, 1999), such as driving. So in short, AD is characterized by a complex cluster of symptoms spanning memory, attentional, linguistic, and executive processes.
Original languageEnglish
Title of host publicationComputational Models of Brain and Behavior
EditorsAhmed A. Moustafa
ISBN (Electronic)978-1-119-15918-6
ISBN (Print)978-1-119-15906-3
Publication statusPublished - 2018
Externally publishedYes


Dive into the research topics of 'Computational Models of Pharmacological and Immunological Treatment in Alzheimer’s Disease'. Together they form a unique fingerprint.

Cite this