Cimetidine and ranitidine in duodenal ulcer

M. Langman; D. A. Henry; G. D. Bell; W. R. Burnham

doi:10.1136/bmj.281.6238.473

Cimetidine and ranitidine in duodenal ulcer

M. Langman, D. A. Henry, G. D. Bell, W. R. Burnham

Research output: Contribution to journal › Article › Research › peer-review

37 Citations (Scopus)

Abstract

Two histamine H2 antagonists, cimetidine and ranitidine, given in doses of 1 g daily and 200 mg daily to 18 and 20 patients respectively proved equivalent in promoting healing of duodenal ulcer. No adverse effects occurred during the trial, though serum urea and creatinine concentrations tended to rise slightly during treatment with cimetidine but not ranitidine. Choice between the two drugs is likely to be influenced by overall patterns of adverse effects rather than considerations of individual potency.

Original language	English
Pages (from-to)	473-474
Number of pages	2
Journal	British Medical Journal
Volume	281
Issue number	6238
DOIs	https://doi.org/10.1136/bmj.281.6238.473
Publication status	Published - Aug 1980
Externally published	Yes

Access to Document

10.1136/bmj.281.6238.473Licence: Free to read

Cite this

@article{52f10cf30a074e2ebd0e82e8acfba985,

title = "Cimetidine and ranitidine in duodenal ulcer",

abstract = "Two histamine H2 antagonists, cimetidine and ranitidine, given in doses of 1 g daily and 200 mg daily to 18 and 20 patients respectively proved equivalent in promoting healing of duodenal ulcer. No adverse effects occurred during the trial, though serum urea and creatinine concentrations tended to rise slightly during treatment with cimetidine but not ranitidine. Choice between the two drugs is likely to be influenced by overall patterns of adverse effects rather than considerations of individual potency.",

author = "M. Langman and Henry, {D. A.} and Bell, {G. D.} and Burnham, {W. R.}",

year = "1980",

month = aug,

doi = "10.1136/bmj.281.6238.473",

language = "English",

volume = "281",

pages = "473--474",

journal = "British Medical Journal",

issn = "0007-1447",

publisher = "BMJ Publishing Group",

number = "6238",

}

TY - JOUR

T1 - Cimetidine and ranitidine in duodenal ulcer

AU - Langman, M.

AU - Henry, D. A.

AU - Bell, G. D.

AU - Burnham, W. R.

PY - 1980/8

Y1 - 1980/8

N2 - Two histamine H2 antagonists, cimetidine and ranitidine, given in doses of 1 g daily and 200 mg daily to 18 and 20 patients respectively proved equivalent in promoting healing of duodenal ulcer. No adverse effects occurred during the trial, though serum urea and creatinine concentrations tended to rise slightly during treatment with cimetidine but not ranitidine. Choice between the two drugs is likely to be influenced by overall patterns of adverse effects rather than considerations of individual potency.

AB - Two histamine H2 antagonists, cimetidine and ranitidine, given in doses of 1 g daily and 200 mg daily to 18 and 20 patients respectively proved equivalent in promoting healing of duodenal ulcer. No adverse effects occurred during the trial, though serum urea and creatinine concentrations tended to rise slightly during treatment with cimetidine but not ranitidine. Choice between the two drugs is likely to be influenced by overall patterns of adverse effects rather than considerations of individual potency.

UR - http://www.scopus.com/inward/record.url?scp=0018851048&partnerID=8YFLogxK

U2 - 10.1136/bmj.281.6238.473

DO - 10.1136/bmj.281.6238.473

M3 - Article

C2 - 6107154

AN - SCOPUS:0018851048

SN - 0007-1447

VL - 281

SP - 473

EP - 474

JO - British Medical Journal

JF - British Medical Journal

IS - 6238

ER -

Cimetidine and ranitidine in duodenal ulcer

Abstract

Access to Document

Other files and links

Fingerprint

Cite this