Cimetidine and ranitidine in duodenal ulcer

M. Langman, D. A. Henry, G. D. Bell, W. R. Burnham

Research output: Contribution to journalArticleResearchpeer-review

37 Citations (Scopus)


Two histamine H2 antagonists, cimetidine and ranitidine, given in doses of 1 g daily and 200 mg daily to 18 and 20 patients respectively proved equivalent in promoting healing of duodenal ulcer. No adverse effects occurred during the trial, though serum urea and creatinine concentrations tended to rise slightly during treatment with cimetidine but not ranitidine. Choice between the two drugs is likely to be influenced by overall patterns of adverse effects rather than considerations of individual potency.

Original languageEnglish
Pages (from-to)473-474
Number of pages2
JournalBritish Medical Journal
Issue number6238
Publication statusPublished - Aug 1980
Externally publishedYes


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