Abstract
Introduction. Cholinergic control of the prostate is not well understood. Muscarinic receptors are thought to be
involved in contraction, secretion and proliferation, although studies of human prostate have been contradictory,
showing the presence of M1, M2 or both receptors (Ruggieri et al. 1995; Yazawa et al. 1994; Anisuzzaman et al.
2008) and M3 receptors in cell lines (Rayford et al. 1997).
Aim. To characterise the muscarinic receptors present in human prostate using radioligand binding and a range of
muscarinic receptor antagonists.
involved in contraction, secretion and proliferation, although studies of human prostate have been contradictory,
showing the presence of M1, M2 or both receptors (Ruggieri et al. 1995; Yazawa et al. 1994; Anisuzzaman et al.
2008) and M3 receptors in cell lines (Rayford et al. 1997).
Aim. To characterise the muscarinic receptors present in human prostate using radioligand binding and a range of
muscarinic receptor antagonists.
| Original language | English |
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| Publication status | Published - 2011 |
| Event | ASCEPT-AuPS-HBPRCA Joint Meeting Program - Perth, Australia Duration: 4 Dec 2011 → 9 Dec 2011 |
Conference
| Conference | ASCEPT-AuPS-HBPRCA Joint Meeting Program |
|---|---|
| Country/Territory | Australia |
| City | Perth |
| Period | 4/12/11 → 9/12/11 |