Characterisation of Muscarinic Receptor Substypes in the Prostate by Radioligand Binding

Research output: Contribution to conferenceAbstractResearch

Abstract

Introduction. Cholinergic control of the prostate is not well understood. Muscarinic receptors are thought to be
involved in contraction, secretion and proliferation, although studies of human prostate have been contradictory,
showing the presence of M1, M2 or both receptors (Ruggieri et al. 1995; Yazawa et al. 1994; Anisuzzaman et al.
2008) and M3 receptors in cell lines (Rayford et al. 1997).
Aim. To characterise the muscarinic receptors present in human prostate using radioligand binding and a range of
muscarinic receptor antagonists.
Original languageEnglish
Publication statusPublished - 2011
EventASCEPT-AuPS-HBPRCA Joint Meeting Program - Perth, Australia
Duration: 4 Dec 20119 Dec 2011

Conference

ConferenceASCEPT-AuPS-HBPRCA Joint Meeting Program
CountryAustralia
CityPerth
Period4/12/119/12/11

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Sellers, D. J., Warre, R., & Chess-Williams, R. (2011). Characterisation of Muscarinic Receptor Substypes in the Prostate by Radioligand Binding. Abstract from ASCEPT-AuPS-HBPRCA Joint Meeting Program , Perth, Australia.