Caffeine improves supramaximal cycling but not the rate of anaerobic energy release

Michael J. Simmonds, Clare L. Minahan, Surendran Sabapathy

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57 Citations (Scopus)


The purpose of this study was to determine if improved supramaximal exercise performance in trained cyclists following caffeine ingestion was associated with enhanced O2 uptake (V̇O2 kinetics), increased anaerobic energy provision (accumulated O2-AO 2-deficit), or a reduction in the accumulation of metabolites (for example, K+) associated with muscular fatigue. Six highly trained male cyclists (V̇O2 peak 68 ± 8 mL kg-1 min-1) performed supramaximal (120% V̇O2peak) exercise bouts to exhaustion on an electronically braked cycle ergometer, following double-blind and randomized ingestion of caffeine/placebo (5 mg kg -1). Time to exhaustion (TE), V̇2 kinetics, AO 2 deficit, blood lactate (La-), plasma potassium (K +), caffeine and paraxanthine concentrations were measured. Caffeine ingestion elicited significant increases in TE (14.8%, p < 0.01) and AO 2 deficit (6.5%, p < 0.05). In contrast, no changes were observed in AO2 deficit at isotime, V̇O2 kinetics, blood [La-] at exhaustion or peak [K+] following caffeine ingestion. However, [K+] was significantly reduced (13.4%, p < 0.01) during warm-up cycling immediately prior to the onset of the supramaximal bout for the caffeine trials, compared with placebo. It appears that caffeine ingestion is beneficial to supramaximal cycling performance in highly trained men. The reduced plasma [K+] during submaximal warm-up cycling may prolong the time taken to reach critical [K+] at exhaustion, thus delaying fatigue. Considering caffeine ingestion did not change V̇O 2 kinetics or isotime AO2 deficit, increases in absolute AO2 deficit may be a consequence of prolonged TE, rather than causal.

Original languageEnglish
Pages (from-to)287-295
Number of pages9
JournalEuropean Journal of Applied Physiology
Issue number2
Publication statusPublished - May 2010
Externally publishedYes


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