Binding of the BL/VL3 murine T cell lymphoma to radiation leukaemia virus is specific for viral env determinants

H C O'Neill

doi:10.1099/0022-1317-72-7-1725

Binding of the BL/VL3 murine T cell lymphoma to radiation leukaemia virus is specific for viral env determinants

H C O'Neill

Research output: Contribution to journal › Article › Research › peer-review

3 Citations (Scopus)

Abstract

Molecularly cloned radiation leukaemia viruses (RadLVs) isolated from the BL/VL3 radiation-induced thymoma have been used in assays to compare the binding specificity of the BL/VL3 cell line for different retroviruses. BL/VL3 cells bound well to two of three thymotropic, leukaemogenic viruses produced by this cell line. BL/VL3 did not bind to a cloned fibrotropic, non-leukaemogenic RadLV. BL/VL3 appears to have receptor specificity for only some of the leukaemogenic RadLVs, and this appears to be related to differences in the viral env sequence.

Original language	English
Pages (from-to)	1725-1728
Number of pages	4
Journal	Journal of General Virology
Volume	72
Issue number	7
DOIs	https://doi.org/10.1099/0022-1317-72-7-1725
Publication status	Published - Jul 1991
Externally published	Yes

Access to Document

10.1099/0022-1317-72-7-1725Licence: Free to read

Cite this

@article{736fe99002c4422490128a67d7a4ab55,

title = "Binding of the BL/VL3 murine T cell lymphoma to radiation leukaemia virus is specific for viral env determinants",

abstract = "Molecularly cloned radiation leukaemia viruses (RadLVs) isolated from the BL/VL3 radiation-induced thymoma have been used in assays to compare the binding specificity of the BL/VL3 cell line for different retroviruses. BL/VL3 cells bound well to two of three thymotropic, leukaemogenic viruses produced by this cell line. BL/VL3 did not bind to a cloned fibrotropic, non-leukaemogenic RadLV. BL/VL3 appears to have receptor specificity for only some of the leukaemogenic RadLVs, and this appears to be related to differences in the viral env sequence.",

author = "O'Neill, {H C}",

year = "1991",

month = jul,

doi = "10.1099/0022-1317-72-7-1725",

language = "English",

volume = "72 ",

pages = "1725--1728",

journal = "Journal of General Virology",

issn = "0022-1317",

publisher = "Society for General Microbiology",

number = "7",

}

TY - JOUR

T1 - Binding of the BL/VL3 murine T cell lymphoma to radiation leukaemia virus is specific for viral env determinants

AU - O'Neill, H C

PY - 1991/7

Y1 - 1991/7

N2 - Molecularly cloned radiation leukaemia viruses (RadLVs) isolated from the BL/VL3 radiation-induced thymoma have been used in assays to compare the binding specificity of the BL/VL3 cell line for different retroviruses. BL/VL3 cells bound well to two of three thymotropic, leukaemogenic viruses produced by this cell line. BL/VL3 did not bind to a cloned fibrotropic, non-leukaemogenic RadLV. BL/VL3 appears to have receptor specificity for only some of the leukaemogenic RadLVs, and this appears to be related to differences in the viral env sequence.

AB - Molecularly cloned radiation leukaemia viruses (RadLVs) isolated from the BL/VL3 radiation-induced thymoma have been used in assays to compare the binding specificity of the BL/VL3 cell line for different retroviruses. BL/VL3 cells bound well to two of three thymotropic, leukaemogenic viruses produced by this cell line. BL/VL3 did not bind to a cloned fibrotropic, non-leukaemogenic RadLV. BL/VL3 appears to have receptor specificity for only some of the leukaemogenic RadLVs, and this appears to be related to differences in the viral env sequence.

U2 - 10.1099/0022-1317-72-7-1725

DO - 10.1099/0022-1317-72-7-1725

M3 - Article

C2 - 1856699

SN - 0022-1317

VL - 72

SP - 1725

EP - 1728

JO - Journal of General Virology

JF - Journal of General Virology

IS - 7

ER -

Binding of the BL/VL3 murine T cell lymphoma to radiation leukaemia virus is specific for viral env determinants

Abstract

Access to Document

Fingerprint

Cite this