Binding of the BL/VL3 murine T cell lymphoma to radiation leukaemia virus is specific for viral env determinants

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Abstract

Molecularly cloned radiation leukaemia viruses (RadLVs) isolated from the BL/VL3 radiation-induced thymoma have been used in assays to compare the binding specificity of the BL/VL3 cell line for different retroviruses. BL/VL3 cells bound well to two of three thymotropic, leukaemogenic viruses produced by this cell line. BL/VL3 did not bind to a cloned fibrotropic, non-leukaemogenic RadLV. BL/VL3 appears to have receptor specificity for only some of the leukaemogenic RadLVs, and this appears to be related to differences in the viral env sequence.

Original languageEnglish
Pages (from-to)1725-1728
Number of pages4
JournalJournal of General Virology
Volume72
Issue number7
DOIs
Publication statusPublished - Jul 1991
Externally publishedYes

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Radiation Leukemia Virus
T-Cell Lymphoma
Cell Line
Thymoma
Retroviridae
Radiation
Viruses

Cite this

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title = "Binding of the BL/VL3 murine T cell lymphoma to radiation leukaemia virus is specific for viral env determinants",
abstract = "Molecularly cloned radiation leukaemia viruses (RadLVs) isolated from the BL/VL3 radiation-induced thymoma have been used in assays to compare the binding specificity of the BL/VL3 cell line for different retroviruses. BL/VL3 cells bound well to two of three thymotropic, leukaemogenic viruses produced by this cell line. BL/VL3 did not bind to a cloned fibrotropic, non-leukaemogenic RadLV. BL/VL3 appears to have receptor specificity for only some of the leukaemogenic RadLVs, and this appears to be related to differences in the viral env sequence.",
author = "O'Neill, {H C}",
year = "1991",
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Binding of the BL/VL3 murine T cell lymphoma to radiation leukaemia virus is specific for viral env determinants. / O'Neill, H C.

In: Journal of General Virology, Vol. 72 , No. 7, 07.1991, p. 1725-1728.

Research output: Contribution to journalArticleResearchpeer-review

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T1 - Binding of the BL/VL3 murine T cell lymphoma to radiation leukaemia virus is specific for viral env determinants

AU - O'Neill, H C

PY - 1991/7

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N2 - Molecularly cloned radiation leukaemia viruses (RadLVs) isolated from the BL/VL3 radiation-induced thymoma have been used in assays to compare the binding specificity of the BL/VL3 cell line for different retroviruses. BL/VL3 cells bound well to two of three thymotropic, leukaemogenic viruses produced by this cell line. BL/VL3 did not bind to a cloned fibrotropic, non-leukaemogenic RadLV. BL/VL3 appears to have receptor specificity for only some of the leukaemogenic RadLVs, and this appears to be related to differences in the viral env sequence.

AB - Molecularly cloned radiation leukaemia viruses (RadLVs) isolated from the BL/VL3 radiation-induced thymoma have been used in assays to compare the binding specificity of the BL/VL3 cell line for different retroviruses. BL/VL3 cells bound well to two of three thymotropic, leukaemogenic viruses produced by this cell line. BL/VL3 did not bind to a cloned fibrotropic, non-leukaemogenic RadLV. BL/VL3 appears to have receptor specificity for only some of the leukaemogenic RadLVs, and this appears to be related to differences in the viral env sequence.

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DO - 10.1099/0022-1317-72-7-1725

M3 - Article

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JO - Journal of General Virology

JF - Journal of General Virology

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