Benefits of early feeding versus traditional nil-by-mouth nutritional postoperative management in gastrointestinal resectional surgery patients: A meta-analysis

Emma J Osland, Belal Hossain, Shahjahan Khan, Muhammed Memon

Research output: Contribution to conferencePaperResearchpeer-review

Abstract

The objective of the current work was to conduct a meta-analysis of randomized controlled trials evaluating the effect on surgical outcomes of providing nutrition within 24-hours following gastrointestinal surgery compared with traditional postoperative management. A literature search was conducted to identify randomized controlled trials published in English language between1966 and 2007 comparing the outcomes of early and traditional postoperative feeding. All trials involving resection of the portions of the gastrointestinal tract followed by patients receiving nutritionally significant oral or enteral intake within 24-hours after surgery were included for analysis. Random effects meta-analyses were performed. Outcome variables analyzed were complications, mortality, anastomotic dehiscence, nasogastric reinsertion, days to passing flatus, days to first bowel motion, and length of stay. Fifteen studies (n=1240 patients) were analyzed. A statistically significant forty-five percent reduction in relative odds of total postoperative complications were seen in patients receiving early postoperative feeding (OR 0.55CI 0.35, 0.87, p=0.01). No effect of early feeding was seen with relation to anastomotic dehiscence (OR 0.75, CI 0.39, 1.4, p=0.39), mortality (OR 0.71, CI 0.32,1.56, p= 0.39), resumption of bowel function as evidenced by days to passage of flatus (WMD -0.42, CI -1.12, 0.28, p=0.23) and first bowel motion (WMD -0.28, CI -1.20, 0.64, p=0.55), or reduced length of 122 stay (WMD -1.28, CI -2.94, 0.38, p=0.13).
Original languageEnglish
Pages121-131
Number of pages11
Publication statusPublished - 2010
EventTenth Islamic Countries Conference on Statistical Science: Statistics for development and good governance - Cairo, Egypt
Duration: 20 Dec 200923 Dec 2009
Conference number: 10
https://www.iccs-x.org.eg

Conference

ConferenceTenth Islamic Countries Conference on Statistical Science
CountryEgypt
CityCairo
Period20/12/0923/12/09
Internet address

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Flatulence
Mouth
Meta-Analysis
Length of Stay
Randomized Controlled Trials
Mortality
Small Intestine
Gastrointestinal Tract
Language
Odds Ratio

Cite this

Osland, E. J., Hossain, B., Khan, S., & Memon, M. (2010). Benefits of early feeding versus traditional nil-by-mouth nutritional postoperative management in gastrointestinal resectional surgery patients: A meta-analysis. 121-131. Paper presented at Tenth Islamic Countries Conference on Statistical Science, Cairo, Egypt.
Osland, Emma J ; Hossain, Belal ; Khan, Shahjahan ; Memon, Muhammed. / Benefits of early feeding versus traditional nil-by-mouth nutritional postoperative management in gastrointestinal resectional surgery patients : A meta-analysis. Paper presented at Tenth Islamic Countries Conference on Statistical Science, Cairo, Egypt.11 p.
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Osland, EJ, Hossain, B, Khan, S & Memon, M 2010, 'Benefits of early feeding versus traditional nil-by-mouth nutritional postoperative management in gastrointestinal resectional surgery patients: A meta-analysis' Paper presented at Tenth Islamic Countries Conference on Statistical Science, Cairo, Egypt, 20/12/09 - 23/12/09, pp. 121-131.

Benefits of early feeding versus traditional nil-by-mouth nutritional postoperative management in gastrointestinal resectional surgery patients : A meta-analysis. / Osland, Emma J; Hossain, Belal; Khan, Shahjahan; Memon, Muhammed.

2010. 121-131 Paper presented at Tenth Islamic Countries Conference on Statistical Science, Cairo, Egypt.

Research output: Contribution to conferencePaperResearchpeer-review

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T1 - Benefits of early feeding versus traditional nil-by-mouth nutritional postoperative management in gastrointestinal resectional surgery patients

T2 - A meta-analysis

AU - Osland, Emma J

AU - Hossain, Belal

AU - Khan, Shahjahan

AU - Memon, Muhammed

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N2 - The objective of the current work was to conduct a meta-analysis of randomized controlled trials evaluating the effect on surgical outcomes of providing nutrition within 24-hours following gastrointestinal surgery compared with traditional postoperative management. A literature search was conducted to identify randomized controlled trials published in English language between1966 and 2007 comparing the outcomes of early and traditional postoperative feeding. All trials involving resection of the portions of the gastrointestinal tract followed by patients receiving nutritionally significant oral or enteral intake within 24-hours after surgery were included for analysis. Random effects meta-analyses were performed. Outcome variables analyzed were complications, mortality, anastomotic dehiscence, nasogastric reinsertion, days to passing flatus, days to first bowel motion, and length of stay. Fifteen studies (n=1240 patients) were analyzed. A statistically significant forty-five percent reduction in relative odds of total postoperative complications were seen in patients receiving early postoperative feeding (OR 0.55CI 0.35, 0.87, p=0.01). No effect of early feeding was seen with relation to anastomotic dehiscence (OR 0.75, CI 0.39, 1.4, p=0.39), mortality (OR 0.71, CI 0.32,1.56, p= 0.39), resumption of bowel function as evidenced by days to passage of flatus (WMD -0.42, CI -1.12, 0.28, p=0.23) and first bowel motion (WMD -0.28, CI -1.20, 0.64, p=0.55), or reduced length of 122 stay (WMD -1.28, CI -2.94, 0.38, p=0.13).

AB - The objective of the current work was to conduct a meta-analysis of randomized controlled trials evaluating the effect on surgical outcomes of providing nutrition within 24-hours following gastrointestinal surgery compared with traditional postoperative management. A literature search was conducted to identify randomized controlled trials published in English language between1966 and 2007 comparing the outcomes of early and traditional postoperative feeding. All trials involving resection of the portions of the gastrointestinal tract followed by patients receiving nutritionally significant oral or enteral intake within 24-hours after surgery were included for analysis. Random effects meta-analyses were performed. Outcome variables analyzed were complications, mortality, anastomotic dehiscence, nasogastric reinsertion, days to passing flatus, days to first bowel motion, and length of stay. Fifteen studies (n=1240 patients) were analyzed. A statistically significant forty-five percent reduction in relative odds of total postoperative complications were seen in patients receiving early postoperative feeding (OR 0.55CI 0.35, 0.87, p=0.01). No effect of early feeding was seen with relation to anastomotic dehiscence (OR 0.75, CI 0.39, 1.4, p=0.39), mortality (OR 0.71, CI 0.32,1.56, p= 0.39), resumption of bowel function as evidenced by days to passage of flatus (WMD -0.42, CI -1.12, 0.28, p=0.23) and first bowel motion (WMD -0.28, CI -1.20, 0.64, p=0.55), or reduced length of 122 stay (WMD -1.28, CI -2.94, 0.38, p=0.13).

M3 - Paper

SP - 121

EP - 131

ER -

Osland EJ, Hossain B, Khan S, Memon M. Benefits of early feeding versus traditional nil-by-mouth nutritional postoperative management in gastrointestinal resectional surgery patients: A meta-analysis. 2010. Paper presented at Tenth Islamic Countries Conference on Statistical Science, Cairo, Egypt.