Abstract
Urinary urgency is the key sensory symptom of overactive bladder syndrome (OABS). In recent years, injection of botulinum toxin type A (BoNT/A) into the bladder has proved to be an effective way of treating urgency in patients with OABS.
However, the underlying mechanism of action of BoNT/A is unclear. It has been suggested that the efficacy of BoNT/A may
depend on inhibition of vesicular release of neurotransmitters and mediators from suburothelial nerves and/or the urothelium.
However, the underlying mechanism of action of BoNT/A is unclear. It has been suggested that the efficacy of BoNT/A may
depend on inhibition of vesicular release of neurotransmitters and mediators from suburothelial nerves and/or the urothelium.
Original language | English |
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Article number | 126 |
Pages (from-to) | 72-72 |
Number of pages | 1 |
Journal | European Urology, Supplements |
Volume | 9 |
Issue number | 2 |
DOIs | |
Publication status | Published - 2010 |
Externally published | Yes |