Associations between reduced telomere length, depressed mood, anhedonia, and irritability in prostate cancer patients: Further evidence for the presence of "male depression"?

Christopher F. Sharpley, David R.H. Christie, Vicki Bitsika, Linda L. Agnew, Nicholas M. Andronicos, Mary E. Mcmillan

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Extract:
Introduction:
The link between chronic stress and depression has been established
for some time. Major physical illness represents such a chronic
stressor, and people who suffer from such illnesses have been shown
to be at an increased risk of developing depression.Perhaps, one of
the most feared of all illnesses is cancer. Among Australian men, the
most common form of cancer is prostate cancer (PCa). Meta‐analytic
data indicate that PCa patients suffer depression at a prevalence of
18.44% following treatment, several times higher than the 3% to 4%
prevalence in men of similar ages from the general population.
Depression in PCa patients adds to their overall disease burden and
may also impede their recovery from PCa. Although most of the endpoints
that have been measured in studies of depression in these men
have been associated with medical and surgical costs, plus mortality,
the links with the wider biological consequences of this elevated
depression are also of value when formulating a comprehensive model
of PCa depression.
Original languageEnglish
Pages (from-to)1072-1074
Number of pages3
JournalPsycho-Oncology
Volume27
Issue number3
DOIs
Publication statusE-pub ahead of print - 30 Aug 2017

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Anhedonia
Telomere
Prostatic Neoplasms
Depression
Costs and Cost Analysis
Mortality
Population
Neoplasms

Cite this

Sharpley, Christopher F. ; Christie, David R.H. ; Bitsika, Vicki ; Agnew, Linda L. ; Andronicos, Nicholas M. ; Mcmillan, Mary E. / Associations between reduced telomere length, depressed mood, anhedonia, and irritability in prostate cancer patients: Further evidence for the presence of "male depression"?. In: Psycho-Oncology. 2017 ; Vol. 27, No. 3. pp. 1072-1074.
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abstract = "Extract: Introduction: The link between chronic stress and depression has been establishedfor some time. Major physical illness represents such a chronicstressor, and people who suffer from such illnesses have been shownto be at an increased risk of developing depression.Perhaps, one ofthe most feared of all illnesses is cancer. Among Australian men, themost common form of cancer is prostate cancer (PCa). Meta‐analyticdata indicate that PCa patients suffer depression at a prevalence of18.44{\%} following treatment, several times higher than the 3{\%} to 4{\%}prevalence in men of similar ages from the general population.Depression in PCa patients adds to their overall disease burden andmay also impede their recovery from PCa. Although most of the endpointsthat have been measured in studies of depression in these menhave been associated with medical and surgical costs, plus mortality,the links with the wider biological consequences of this elevateddepression are also of value when formulating a comprehensive modelof PCa depression.",
author = "Sharpley, {Christopher F.} and Christie, {David R.H.} and Vicki Bitsika and Agnew, {Linda L.} and Andronicos, {Nicholas M.} and Mcmillan, {Mary E.}",
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Associations between reduced telomere length, depressed mood, anhedonia, and irritability in prostate cancer patients: Further evidence for the presence of "male depression"? / Sharpley, Christopher F.; Christie, David R.H.; Bitsika, Vicki; Agnew, Linda L.; Andronicos, Nicholas M.; Mcmillan, Mary E.

In: Psycho-Oncology, Vol. 27, No. 3, 30.08.2017, p. 1072-1074.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Associations between reduced telomere length, depressed mood, anhedonia, and irritability in prostate cancer patients: Further evidence for the presence of "male depression"?

AU - Sharpley, Christopher F.

AU - Christie, David R.H.

AU - Bitsika, Vicki

AU - Agnew, Linda L.

AU - Andronicos, Nicholas M.

AU - Mcmillan, Mary E.

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AB - Extract: Introduction: The link between chronic stress and depression has been establishedfor some time. Major physical illness represents such a chronicstressor, and people who suffer from such illnesses have been shownto be at an increased risk of developing depression.Perhaps, one ofthe most feared of all illnesses is cancer. Among Australian men, themost common form of cancer is prostate cancer (PCa). Meta‐analyticdata indicate that PCa patients suffer depression at a prevalence of18.44% following treatment, several times higher than the 3% to 4%prevalence in men of similar ages from the general population.Depression in PCa patients adds to their overall disease burden andmay also impede their recovery from PCa. Although most of the endpointsthat have been measured in studies of depression in these menhave been associated with medical and surgical costs, plus mortality,the links with the wider biological consequences of this elevateddepression are also of value when formulating a comprehensive modelof PCa depression.

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