Associations between Device-measured Physical Activity and Cardiometabolic Health in the Transition to Early Adulthood

Gregore I. Mielke, Ana M.B. Menezes, Bruna Gonçalves C. DA Silva, Ulf Ekelund, Inacio Crochemore-Silva, Fernando C. Wehrmeister, Helen Gonçalves, Wendy J. Brown

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)


PURPOSES: The aims of this study were to investigate the cross-sectional and prospective associations between accelerometer-measured physical activity and cardiometabolic health in the transition to adulthood. 

METHODS: Data from the 1993 Pelotas (Brazil) Birth Cohort were analyzed (n = 2280). Moderate-to-vigorous intensity physical activity (MVPA) (measured using a triaxial accelerometer) and cardiometabolic health (total fat mass, blood glucose, non-high-density lipoprotein cholesterol, triglycerides, and mean resting blood pressure) were examined at age 18 and 22 yr. 

RESULTS: Overall, inverse dose-response associations between MVPA and cardiometabolic health at age 18 and 22 yr were observed in cross-sectional analyses of data from men and women. Prospective analyses showed that, in general, MVPA declined, and cardiometabolic health worsened in this 4-yr period in both men and women. Cardiometabolic health at age 22 yr reflected both MVPA at age 18 yr (β, -0.007; 95% confidence interval [CI], -0.014 to 0.000) and changes in MVPA from 18 to 22 yr (β, -0.030; 95% CI, -0.043 to -0.016) in men, but only changes in MVPA in women (β, -0.035; 95% CI, -0.058 to -0.011). In analyses of change over time, men who improved MVPA by 20 to 30 min·d-1 showed significant improvements in cardiometabolic health over 4 yr. The magnitude of association was slightly stronger for MVPA in 10-min bouts than for MVPA accumulated in bouts of 1 min, especially in women. 

CONCLUSIONS: Moderate-to-vigorous intensity physical activity is an important predictor of cardiometabolic health in early adulthood. Strategies to prevent declines in MVPA at this life stage are required to prevent deteriorating cardiometabolic health profiles.

Original languageEnglish
Pages (from-to)2076-2085
Number of pages10
JournalMedicine and Science in Sports and Exercise
Issue number10
Publication statusPublished - 1 Oct 2021
Externally publishedYes


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