Assessing the impact of a food supplement on the nutritional status and body composition of HIV-infected Zambian women on ARVs

Rodah M. Zulu, Nuala M. Byrne, Grace K. Munthali, James Chipeta, Ray Handema, Mofu Musonda, Andrew P. Hills

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3 Citations (Scopus)

Abstract

Background: Zambia is a sub-Saharan country with one of the highest prevalence rates of HIV, currently estimated at 14%. Poor nutritional status due to both protein-energy and micronutrient malnutrition has worsened this situation. In an attempt to address this combined problem, the government has instigated a number of strategies, including the provision of antiretroviral (ARV) treatment coupled with the promotion of good nutrition. High-energy protein supplement (HEPS) is particularly promoted; however, the impact of this food supplement on the nutritional status of people living with HIV/AIDS (PLHA) beyond weight gain has not been assessed. Techniques for the assessment of nutritional status utilising objective measures of body composition are not commonly available in Zambia. The aim of this study is therefore to assess the impact of a food supplement on nutritional status using a comprehensive anthropometric protocol including measures of skinfold thickness and circumferences, plus the criterion deuterium dilution technique to assess total body water (TBW) and derive fat-free mass (FFM) and fat mass (FM). Methods/Design. This community-based controlled and longitudinal study aims to recruit 200 HIV-infected females commencing ARV treatment at two clinics in Lusaka, Zambia. Data will be collected at four time points: baseline, 4-month, 8-month and 12-month follow-up visits. Outcome measures to be assessed include body height and weight, body mass index (BMI), body composition, CD4, viral load and micronutrient status. Discussion. This protocol describes a study that will provide a longitudinal assessment of the impact of a food supplement on the nutritional status of HIV-infected females initiating ARVs using a range of anthropometric and body composition assessment techniques. Trial Registration. Pan African Clinical Trial Registry PACTR201108000303396.

Original languageEnglish
Article number714
JournalBMC Public Health
Volume11
DOIs
Publication statusPublished - 2011
Externally publishedYes

Fingerprint

Dietary Supplements
Body Composition
Nutritional Status
Zambia
HIV
Micronutrients
Fats
Indicator Dilution Techniques
Protein-Energy Malnutrition
Skinfold Thickness
Body Height
Body Water
Deuterium
Viral Load
Weight Gain
Longitudinal Studies
Registries
Acquired Immunodeficiency Syndrome
Body Mass Index
Body Weight

Cite this

Zulu, Rodah M. ; Byrne, Nuala M. ; Munthali, Grace K. ; Chipeta, James ; Handema, Ray ; Musonda, Mofu ; Hills, Andrew P. / Assessing the impact of a food supplement on the nutritional status and body composition of HIV-infected Zambian women on ARVs. In: BMC Public Health. 2011 ; Vol. 11.
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abstract = "Background: Zambia is a sub-Saharan country with one of the highest prevalence rates of HIV, currently estimated at 14{\%}. Poor nutritional status due to both protein-energy and micronutrient malnutrition has worsened this situation. In an attempt to address this combined problem, the government has instigated a number of strategies, including the provision of antiretroviral (ARV) treatment coupled with the promotion of good nutrition. High-energy protein supplement (HEPS) is particularly promoted; however, the impact of this food supplement on the nutritional status of people living with HIV/AIDS (PLHA) beyond weight gain has not been assessed. Techniques for the assessment of nutritional status utilising objective measures of body composition are not commonly available in Zambia. The aim of this study is therefore to assess the impact of a food supplement on nutritional status using a comprehensive anthropometric protocol including measures of skinfold thickness and circumferences, plus the criterion deuterium dilution technique to assess total body water (TBW) and derive fat-free mass (FFM) and fat mass (FM). Methods/Design. This community-based controlled and longitudinal study aims to recruit 200 HIV-infected females commencing ARV treatment at two clinics in Lusaka, Zambia. Data will be collected at four time points: baseline, 4-month, 8-month and 12-month follow-up visits. Outcome measures to be assessed include body height and weight, body mass index (BMI), body composition, CD4, viral load and micronutrient status. Discussion. This protocol describes a study that will provide a longitudinal assessment of the impact of a food supplement on the nutritional status of HIV-infected females initiating ARVs using a range of anthropometric and body composition assessment techniques. Trial Registration. Pan African Clinical Trial Registry PACTR201108000303396.",
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Assessing the impact of a food supplement on the nutritional status and body composition of HIV-infected Zambian women on ARVs. / Zulu, Rodah M.; Byrne, Nuala M.; Munthali, Grace K.; Chipeta, James; Handema, Ray; Musonda, Mofu; Hills, Andrew P.

In: BMC Public Health, Vol. 11, 714, 2011.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Assessing the impact of a food supplement on the nutritional status and body composition of HIV-infected Zambian women on ARVs

AU - Zulu, Rodah M.

AU - Byrne, Nuala M.

AU - Munthali, Grace K.

AU - Chipeta, James

AU - Handema, Ray

AU - Musonda, Mofu

AU - Hills, Andrew P.

PY - 2011

Y1 - 2011

N2 - Background: Zambia is a sub-Saharan country with one of the highest prevalence rates of HIV, currently estimated at 14%. Poor nutritional status due to both protein-energy and micronutrient malnutrition has worsened this situation. In an attempt to address this combined problem, the government has instigated a number of strategies, including the provision of antiretroviral (ARV) treatment coupled with the promotion of good nutrition. High-energy protein supplement (HEPS) is particularly promoted; however, the impact of this food supplement on the nutritional status of people living with HIV/AIDS (PLHA) beyond weight gain has not been assessed. Techniques for the assessment of nutritional status utilising objective measures of body composition are not commonly available in Zambia. The aim of this study is therefore to assess the impact of a food supplement on nutritional status using a comprehensive anthropometric protocol including measures of skinfold thickness and circumferences, plus the criterion deuterium dilution technique to assess total body water (TBW) and derive fat-free mass (FFM) and fat mass (FM). Methods/Design. This community-based controlled and longitudinal study aims to recruit 200 HIV-infected females commencing ARV treatment at two clinics in Lusaka, Zambia. Data will be collected at four time points: baseline, 4-month, 8-month and 12-month follow-up visits. Outcome measures to be assessed include body height and weight, body mass index (BMI), body composition, CD4, viral load and micronutrient status. Discussion. This protocol describes a study that will provide a longitudinal assessment of the impact of a food supplement on the nutritional status of HIV-infected females initiating ARVs using a range of anthropometric and body composition assessment techniques. Trial Registration. Pan African Clinical Trial Registry PACTR201108000303396.

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U2 - 10.1186/1471-2458-11-714

DO - 10.1186/1471-2458-11-714

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JO - BMC Public Health

JF - BMC Public Health

SN - 1471-2458

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