Arguments for the ethical permissibility of transgenic xenografting

K. A. Bramstedt*

*Corresponding author for this work

Research output: Contribution to journalEditorialResearch

6 Citations (Scopus)


According to UNOS (United Network for Organ Sharing), 2000 will be another year of severe donor liver shortage for those in the USA awaiting transplant. On 31 October 1999, UNOS reported 66175 registered patients on their national organ transplant waiting list. Of these, 14088 patients are registered for a liver transplant. The 1998 human donor liver pool was only 4487. Previous attempts to address this shortage have included bioartificial livers and extracorporeal liver assist devices,1 permanent whole organ xenotransplants,2 and whole organ
xenotransplant bridges.3 The use of non-transgenic animal organs for whole organ transplantation presents technical dilemmas for scientists, namely hyperacute rejection, however, transgenic animals may be able to address this challenge
Original languageEnglish
Pages (from-to)633-634
Number of pages2
JournalGene Therapy
Issue number8
Publication statusPublished - 2000
Externally publishedYes


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