An Observational Study of Dyspnea in Emergency Departments: The Asia, Australia, and New Zealand Dyspnea in Emergency Departments Study (AANZDEM)

Anne Maree Kelly, Gerben Keijzers, Sharon Klim, Colin A. Graham, Simon Craig, Win Sen Kuan, Peter Jones, Anna Holdgate, Charles Lawoko, Said Laribi

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Abstract

OBJECTIVES: To describe the epidemiology of dyspnoea presenting to emergency departments (EDs) in the Asia-Pacific region, to understand how it is investigated and treated and its outcome.

METHODS: Prospectiveinterrupted time series cohort study conducted at three time points in EDs in Australia, New Zealand, Singapore, Hong Kong and Malaysia of adult patients presenting to the ED with dyspnoea as a main symptom. Data were collected over three 72-hour periods and included demographics, co-morbidities, mode of arrival, usual medications, pre-hospital treatment, initial assessment, ED investigations, treatment in the ED, ED diagnosis, disposition from ED, in-hospital outcome and final hospital diagnosis. The primary outcomes of interest are the epidemiology, investigation, treatment and outcome of patients presenting to ED with dyspnoea.

RESULTS: 3044 patients were studied. Patients with dyspnoea made up 5.2% (3105/60059, 95% CI 5.0-5.4%) of ED presentations, 11.4% of ward admissions (1956/17184, 95% CI 10.9-11.9%) and 19.9% of Intensive Care Unit (ICU) admissions (104/523, 95% CI 16.7-23.5%). The most common diagnoses were lower respiratory tract infection (20.2%), heart failure (14.9%), chronic obstructive pulmonary disease (13.6%) and asthma (12.7%). Hospital ward admission was required for 64% of patients (95% CI 62-66%) with 3.3% (95% CI 2.8-4.1%) requiring ICU admission. In hospital mortality was 6% (95% CI 5.0-7.2%).

CONCLUSION: Dyspnoea is a common symptom in ED patients contributing substantially to ED, hospital and ICU workload. It is also associated with significant mortality. There are a wide variety of causes however chronic disease accounts for a large proportion. This article is protected by copyright. All rights reserved.

Original languageEnglish
Pages (from-to)328-336
Number of pages9
JournalAcademic Emergency Medicine
Volume24
Issue number3
DOIs
Publication statusPublished - 1 Mar 2017

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New Zealand
Dyspnea
Observational Studies
Hospital Emergency Service
Intensive Care Units
Epidemiology
Malaysia
Singapore
Hong Kong
Emergency Medical Services
Hospital Mortality
Workload
Respiratory Tract Infections
Chronic Obstructive Pulmonary Disease
Chronic Disease
Cohort Studies
Asthma
Heart Failure
Demography
Morbidity

Cite this

Kelly, Anne Maree ; Keijzers, Gerben ; Klim, Sharon ; Graham, Colin A. ; Craig, Simon ; Kuan, Win Sen ; Jones, Peter ; Holdgate, Anna ; Lawoko, Charles ; Laribi, Said. / An Observational Study of Dyspnea in Emergency Departments : The Asia, Australia, and New Zealand Dyspnea in Emergency Departments Study (AANZDEM). In: Academic Emergency Medicine. 2017 ; Vol. 24, No. 3. pp. 328-336.
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title = "An Observational Study of Dyspnea in Emergency Departments: The Asia, Australia, and New Zealand Dyspnea in Emergency Departments Study (AANZDEM)",
abstract = "OBJECTIVES: To describe the epidemiology of dyspnoea presenting to emergency departments (EDs) in the Asia-Pacific region, to understand how it is investigated and treated and its outcome.METHODS: Prospectiveinterrupted time series cohort study conducted at three time points in EDs in Australia, New Zealand, Singapore, Hong Kong and Malaysia of adult patients presenting to the ED with dyspnoea as a main symptom. Data were collected over three 72-hour periods and included demographics, co-morbidities, mode of arrival, usual medications, pre-hospital treatment, initial assessment, ED investigations, treatment in the ED, ED diagnosis, disposition from ED, in-hospital outcome and final hospital diagnosis. The primary outcomes of interest are the epidemiology, investigation, treatment and outcome of patients presenting to ED with dyspnoea.RESULTS: 3044 patients were studied. Patients with dyspnoea made up 5.2{\%} (3105/60059, 95{\%} CI 5.0-5.4{\%}) of ED presentations, 11.4{\%} of ward admissions (1956/17184, 95{\%} CI 10.9-11.9{\%}) and 19.9{\%} of Intensive Care Unit (ICU) admissions (104/523, 95{\%} CI 16.7-23.5{\%}). The most common diagnoses were lower respiratory tract infection (20.2{\%}), heart failure (14.9{\%}), chronic obstructive pulmonary disease (13.6{\%}) and asthma (12.7{\%}). Hospital ward admission was required for 64{\%} of patients (95{\%} CI 62-66{\%}) with 3.3{\%} (95{\%} CI 2.8-4.1{\%}) requiring ICU admission. In hospital mortality was 6{\%} (95{\%} CI 5.0-7.2{\%}).CONCLUSION: Dyspnoea is a common symptom in ED patients contributing substantially to ED, hospital and ICU workload. It is also associated with significant mortality. There are a wide variety of causes however chronic disease accounts for a large proportion. This article is protected by copyright. All rights reserved.",
author = "Kelly, {Anne Maree} and Gerben Keijzers and Sharon Klim and Graham, {Colin A.} and Simon Craig and Kuan, {Win Sen} and Peter Jones and Anna Holdgate and Charles Lawoko and Said Laribi",
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An Observational Study of Dyspnea in Emergency Departments : The Asia, Australia, and New Zealand Dyspnea in Emergency Departments Study (AANZDEM). / Kelly, Anne Maree; Keijzers, Gerben; Klim, Sharon; Graham, Colin A.; Craig, Simon; Kuan, Win Sen; Jones, Peter; Holdgate, Anna; Lawoko, Charles; Laribi, Said.

In: Academic Emergency Medicine, Vol. 24, No. 3, 01.03.2017, p. 328-336.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - An Observational Study of Dyspnea in Emergency Departments

T2 - The Asia, Australia, and New Zealand Dyspnea in Emergency Departments Study (AANZDEM)

AU - Kelly, Anne Maree

AU - Keijzers, Gerben

AU - Klim, Sharon

AU - Graham, Colin A.

AU - Craig, Simon

AU - Kuan, Win Sen

AU - Jones, Peter

AU - Holdgate, Anna

AU - Lawoko, Charles

AU - Laribi, Said

N1 - This article is protected by copyright. All rights reserved.

PY - 2017/3/1

Y1 - 2017/3/1

N2 - OBJECTIVES: To describe the epidemiology of dyspnoea presenting to emergency departments (EDs) in the Asia-Pacific region, to understand how it is investigated and treated and its outcome.METHODS: Prospectiveinterrupted time series cohort study conducted at three time points in EDs in Australia, New Zealand, Singapore, Hong Kong and Malaysia of adult patients presenting to the ED with dyspnoea as a main symptom. Data were collected over three 72-hour periods and included demographics, co-morbidities, mode of arrival, usual medications, pre-hospital treatment, initial assessment, ED investigations, treatment in the ED, ED diagnosis, disposition from ED, in-hospital outcome and final hospital diagnosis. The primary outcomes of interest are the epidemiology, investigation, treatment and outcome of patients presenting to ED with dyspnoea.RESULTS: 3044 patients were studied. Patients with dyspnoea made up 5.2% (3105/60059, 95% CI 5.0-5.4%) of ED presentations, 11.4% of ward admissions (1956/17184, 95% CI 10.9-11.9%) and 19.9% of Intensive Care Unit (ICU) admissions (104/523, 95% CI 16.7-23.5%). The most common diagnoses were lower respiratory tract infection (20.2%), heart failure (14.9%), chronic obstructive pulmonary disease (13.6%) and asthma (12.7%). Hospital ward admission was required for 64% of patients (95% CI 62-66%) with 3.3% (95% CI 2.8-4.1%) requiring ICU admission. In hospital mortality was 6% (95% CI 5.0-7.2%).CONCLUSION: Dyspnoea is a common symptom in ED patients contributing substantially to ED, hospital and ICU workload. It is also associated with significant mortality. There are a wide variety of causes however chronic disease accounts for a large proportion. This article is protected by copyright. All rights reserved.

AB - OBJECTIVES: To describe the epidemiology of dyspnoea presenting to emergency departments (EDs) in the Asia-Pacific region, to understand how it is investigated and treated and its outcome.METHODS: Prospectiveinterrupted time series cohort study conducted at three time points in EDs in Australia, New Zealand, Singapore, Hong Kong and Malaysia of adult patients presenting to the ED with dyspnoea as a main symptom. Data were collected over three 72-hour periods and included demographics, co-morbidities, mode of arrival, usual medications, pre-hospital treatment, initial assessment, ED investigations, treatment in the ED, ED diagnosis, disposition from ED, in-hospital outcome and final hospital diagnosis. The primary outcomes of interest are the epidemiology, investigation, treatment and outcome of patients presenting to ED with dyspnoea.RESULTS: 3044 patients were studied. Patients with dyspnoea made up 5.2% (3105/60059, 95% CI 5.0-5.4%) of ED presentations, 11.4% of ward admissions (1956/17184, 95% CI 10.9-11.9%) and 19.9% of Intensive Care Unit (ICU) admissions (104/523, 95% CI 16.7-23.5%). The most common diagnoses were lower respiratory tract infection (20.2%), heart failure (14.9%), chronic obstructive pulmonary disease (13.6%) and asthma (12.7%). Hospital ward admission was required for 64% of patients (95% CI 62-66%) with 3.3% (95% CI 2.8-4.1%) requiring ICU admission. In hospital mortality was 6% (95% CI 5.0-7.2%).CONCLUSION: Dyspnoea is a common symptom in ED patients contributing substantially to ED, hospital and ICU workload. It is also associated with significant mortality. There are a wide variety of causes however chronic disease accounts for a large proportion. This article is protected by copyright. All rights reserved.

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U2 - 10.1111/acem.13118

DO - 10.1111/acem.13118

M3 - Article

VL - 24

SP - 328

EP - 336

JO - Academic Emergency Medicine

JF - Academic Emergency Medicine

SN - 1069-6563

IS - 3

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