An Australian perspective SADI-S/OADS: adverse events and nutritional deficiencies

Jacobus Jordaan, Nova Jordaan, Skye Marshall

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Abstract

Background: The rate of adverse events and the impact of single anastomosis duodenal-ileal bypass with sleeve gastrectomy or one anastomosis duodenal switch (SADI-S/OADS) on nutritional deficiencies has not been reported in the Australian population.
Objectives: To determine the rate of adverse events and nutritional deficiencies in Australians with obesity who received SADI-S/OADS.
Methods: Retrospective cohort study. Adults were eligible if they attended SADI-S/OADS. All patients received an individualised nutritional supplementation regimen.
Results: 85 patients underwent SADI-S/OADS. Eligible patients were 44.7 [S.D. 10.9] years of age, 64.7% female, with an average follow-up of 10.7 months. Baseline serum deficiencies were 91.2% for vitamin D, 26.5% for vitamin A, 5.9% for zinc, 20.6% for iron, 2.9% for albumin; and 0% for protein and vitamins B1, B6, and B12. At follow-up, there was no change the rate of deficiencies for serum vitamin B1 (0%), vitamin B12 (0%), iron (8.8%), protein (5.9%), or albumin (2.9%). The rate of vitamin D (61.8%; p=0.011) deficiency improved; however, the rates of vitamin B6 (23.5%; p=0.008), vitamin A (61.8%; p=0.007), and zinc (29.4%; p=0.009) increased. There were 3 surgical post-operative events: 1 repair inadvertent enterotomy day 1 post-op, 1 wound infection, 1 return to theatre for diagnostic laparoscopy which was unremarkable.
Conclusion: In Australia, initial results suggest SADI-S/OADS has a low rate of adverse events but requires intensive and individualised nutritional supplementation both pre- and post-surgery, and correction of deficiencies prior to surgery should be considered. Long-term follow-up is required.
Original languageEnglish
Article numberPO-345
Pages (from-to)746
JournalObesity Surgery
Volume29
Issue numberS5
Early online date26 Jul 2019
DOIs
Publication statusPublished - Sep 2019
Event24th International Federation for the Surgery of Obesity and Metabolic Disorders World Congress - Madrid, Spain
Duration: 3 Sep 20197 Sep 2019
Conference number: 24th
https://www.ifso2019.com/

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Gastrectomy
Malnutrition
Vitamin B 6
Thiamine
Vitamin B 12
Vitamin A
Vitamin D
Zinc
Albumins
Iron
Wound Infection
Serum
Laparoscopy
Proteins
Cohort Studies
Retrospective Studies
Obesity
Population

Cite this

Jordaan, Jacobus ; Jordaan, Nova ; Marshall, Skye. / An Australian perspective SADI-S/OADS: adverse events and nutritional deficiencies. In: Obesity Surgery. 2019 ; Vol. 29, No. S5. pp. 746.
@article{c7b787a45e204b5497a5af5c24549a99,
title = "An Australian perspective SADI-S/OADS: adverse events and nutritional deficiencies",
abstract = "Background: The rate of adverse events and the impact of single anastomosis duodenal-ileal bypass with sleeve gastrectomy or one anastomosis duodenal switch (SADI-S/OADS) on nutritional deficiencies has not been reported in the Australian population. Objectives: To determine the rate of adverse events and nutritional deficiencies in Australians with obesity who received SADI-S/OADS.Methods: Retrospective cohort study. Adults were eligible if they attended SADI-S/OADS. All patients received an individualised nutritional supplementation regimen.Results: 85 patients underwent SADI-S/OADS. Eligible patients were 44.7 [S.D. 10.9] years of age, 64.7{\%} female, with an average follow-up of 10.7 months. Baseline serum deficiencies were 91.2{\%} for vitamin D, 26.5{\%} for vitamin A, 5.9{\%} for zinc, 20.6{\%} for iron, 2.9{\%} for albumin; and 0{\%} for protein and vitamins B1, B6, and B12. At follow-up, there was no change the rate of deficiencies for serum vitamin B1 (0{\%}), vitamin B12 (0{\%}), iron (8.8{\%}), protein (5.9{\%}), or albumin (2.9{\%}). The rate of vitamin D (61.8{\%}; p=0.011) deficiency improved; however, the rates of vitamin B6 (23.5{\%}; p=0.008), vitamin A (61.8{\%}; p=0.007), and zinc (29.4{\%}; p=0.009) increased. There were 3 surgical post-operative events: 1 repair inadvertent enterotomy day 1 post-op, 1 wound infection, 1 return to theatre for diagnostic laparoscopy which was unremarkable. Conclusion: In Australia, initial results suggest SADI-S/OADS has a low rate of adverse events but requires intensive and individualised nutritional supplementation both pre- and post-surgery, and correction of deficiencies prior to surgery should be considered. Long-term follow-up is required.",
author = "Jacobus Jordaan and Nova Jordaan and Skye Marshall",
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doi = "10.1007/s11695-019-04101-1",
language = "English",
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An Australian perspective SADI-S/OADS: adverse events and nutritional deficiencies. / Jordaan, Jacobus; Jordaan, Nova; Marshall, Skye.

In: Obesity Surgery, Vol. 29, No. S5, PO-345, 09.2019, p. 746.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

TY - JOUR

T1 - An Australian perspective SADI-S/OADS: adverse events and nutritional deficiencies

AU - Jordaan, Jacobus

AU - Jordaan, Nova

AU - Marshall, Skye

N1 - Submitted. Awaiting outcome

PY - 2019/9

Y1 - 2019/9

N2 - Background: The rate of adverse events and the impact of single anastomosis duodenal-ileal bypass with sleeve gastrectomy or one anastomosis duodenal switch (SADI-S/OADS) on nutritional deficiencies has not been reported in the Australian population. Objectives: To determine the rate of adverse events and nutritional deficiencies in Australians with obesity who received SADI-S/OADS.Methods: Retrospective cohort study. Adults were eligible if they attended SADI-S/OADS. All patients received an individualised nutritional supplementation regimen.Results: 85 patients underwent SADI-S/OADS. Eligible patients were 44.7 [S.D. 10.9] years of age, 64.7% female, with an average follow-up of 10.7 months. Baseline serum deficiencies were 91.2% for vitamin D, 26.5% for vitamin A, 5.9% for zinc, 20.6% for iron, 2.9% for albumin; and 0% for protein and vitamins B1, B6, and B12. At follow-up, there was no change the rate of deficiencies for serum vitamin B1 (0%), vitamin B12 (0%), iron (8.8%), protein (5.9%), or albumin (2.9%). The rate of vitamin D (61.8%; p=0.011) deficiency improved; however, the rates of vitamin B6 (23.5%; p=0.008), vitamin A (61.8%; p=0.007), and zinc (29.4%; p=0.009) increased. There were 3 surgical post-operative events: 1 repair inadvertent enterotomy day 1 post-op, 1 wound infection, 1 return to theatre for diagnostic laparoscopy which was unremarkable. Conclusion: In Australia, initial results suggest SADI-S/OADS has a low rate of adverse events but requires intensive and individualised nutritional supplementation both pre- and post-surgery, and correction of deficiencies prior to surgery should be considered. Long-term follow-up is required.

AB - Background: The rate of adverse events and the impact of single anastomosis duodenal-ileal bypass with sleeve gastrectomy or one anastomosis duodenal switch (SADI-S/OADS) on nutritional deficiencies has not been reported in the Australian population. Objectives: To determine the rate of adverse events and nutritional deficiencies in Australians with obesity who received SADI-S/OADS.Methods: Retrospective cohort study. Adults were eligible if they attended SADI-S/OADS. All patients received an individualised nutritional supplementation regimen.Results: 85 patients underwent SADI-S/OADS. Eligible patients were 44.7 [S.D. 10.9] years of age, 64.7% female, with an average follow-up of 10.7 months. Baseline serum deficiencies were 91.2% for vitamin D, 26.5% for vitamin A, 5.9% for zinc, 20.6% for iron, 2.9% for albumin; and 0% for protein and vitamins B1, B6, and B12. At follow-up, there was no change the rate of deficiencies for serum vitamin B1 (0%), vitamin B12 (0%), iron (8.8%), protein (5.9%), or albumin (2.9%). The rate of vitamin D (61.8%; p=0.011) deficiency improved; however, the rates of vitamin B6 (23.5%; p=0.008), vitamin A (61.8%; p=0.007), and zinc (29.4%; p=0.009) increased. There were 3 surgical post-operative events: 1 repair inadvertent enterotomy day 1 post-op, 1 wound infection, 1 return to theatre for diagnostic laparoscopy which was unremarkable. Conclusion: In Australia, initial results suggest SADI-S/OADS has a low rate of adverse events but requires intensive and individualised nutritional supplementation both pre- and post-surgery, and correction of deficiencies prior to surgery should be considered. Long-term follow-up is required.

U2 - 10.1007/s11695-019-04101-1

DO - 10.1007/s11695-019-04101-1

M3 - Meeting Abstract

VL - 29

SP - 746

JO - Obesity Surgery

JF - Obesity Surgery

SN - 0960-8923

IS - S5

M1 - PO-345

ER -