An Australian perspective SADI-S/OADS: adverse events and nutritional deficiencies

Jacobus Jordaan, Nova Jordaan, Skye Marshall

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Abstract

Background: The rate of adverse events and the impact of single anastomosis duodenal-ileal bypass with sleeve gastrectomy or one anastomosis duodenal switch (SADI-S/OADS) on nutritional deficiencies has not been reported in the Australian population.
Objectives: To determine the rate of adverse events and nutritional deficiencies in Australians with obesity who received SADI-S/OADS.
Methods: Retrospective cohort study. Adults were eligible if they attended SADI-S/OADS. All patients received an individualised nutritional supplementation regimen.
Results: 85 patients underwent SADI-S/OADS. Eligible patients were 44.7 [S.D. 10.9] years of age, 64.7% female, with an average follow-up of 10.7 months. Baseline serum deficiencies were 91.2% for vitamin D, 26.5% for vitamin A, 5.9% for zinc, 20.6% for iron, 2.9% for albumin; and 0% for protein and vitamins B1, B6, and B12. At follow-up, there was no change the rate of deficiencies for serum vitamin B1 (0%), vitamin B12 (0%), iron (8.8%), protein (5.9%), or albumin (2.9%). The rate of vitamin D (61.8%; p=0.011) deficiency improved; however, the rates of vitamin B6 (23.5%; p=0.008), vitamin A (61.8%; p=0.007), and zinc (29.4%; p=0.009) increased. There were 3 surgical post-operative events: 1 repair inadvertent enterotomy day 1 post-op, 1 wound infection, 1 return to theatre for diagnostic laparoscopy which was unremarkable.
Conclusion: In Australia, initial results suggest SADI-S/OADS has a low rate of adverse events but requires intensive and individualised nutritional supplementation both pre- and post-surgery, and correction of deficiencies prior to surgery should be considered. Long-term follow-up is required.
Original languageEnglish
Article numberPO-345
Pages (from-to)746
JournalObesity Surgery
Volume29
Issue numberS5
Early online date26 Jul 2019
DOIs
Publication statusPublished - Sep 2019
Event24th International Federation for the Surgery of Obesity and Metabolic Disorders World Congress - Madrid, Spain
Duration: 3 Sep 20197 Sep 2019
Conference number: 24th
https://www.ifso2019.com/

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    Marshall, S., Isenring, E., MacKenzie-Shalders, K., Kelly, J., Campbell, K., Van der Meij, B., Cox, G., Reidlinger, D., Mayr, H., Banbury, M., Nucera, R., Jenkins, J., McCray, S., Canavan, R., Parker, B., de Groot, L., Cohen, F., Rich, G., Soni, A., McCarthy, A. L., Mackay, H., Young, A. M., Hickman, I., Wilkinson, S. A., Kiss, N. & Ali, A.

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