Adaptations to short-term high-fat diet persist during exercise despite high carbohydrate availability

Louise M. Burke*, John A. Hawley, Damien J. Angus, Gregory R. Cox, Sally A. Clark, Nicola K. Cummings, Ben Desbrow, Mark Hargreaves

*Corresponding author for this work

Research output: Contribution to journalArticleResearchpeer-review

88 Citations (Scopus)

Abstract

Purpose: Five days of a high-fat diet produce metabolic adaptations that increase the rate of fat oxidation during prolonged exercise. We investigated whether enhanced rates of fat oxidation during submaximal exercise after 5 d of a high-fat diet would persist in the face of increased carbohydrate (CHO) availability before and during exercise. Methods: Eight well-trained subjects consumed either a high-CHO (9.3 g·kg-1·d-1 CHO, 1.1 g·kg-1·d-1 fat; HCHO) or an isoenergetic high-fat diet (2.5 g·kg-1·d-1 CHO, 4.3 g·kg-1·d-1 fat; FAT-adapt) for 5 d followed by a high-CHO diet and rest on day 6. On day 7, performance testing (2 h steady-state (SS) cycling at 70% peak O2 uptake [V̇O2peak] + time trial [TT]) of 7 kJ·kg-1) was undertaken after a CHO breakfast (CHO 2 g·kg-1) and intake of CHO during cycling (0.8 g·kg-1·h-1). Results: FAT-adapt reduced respiratory exchange ratio (RER) values before and during cycling at 70% V̇O2peak; RER was restored by I d CHO and CHO intake during cycling (0.90 ± 0.01, 0.8 ± 0.01, 0.91 ± 0.01, for days 1, 6, and 7, respectively). RER values were higher with HCHO (0.90 ± 0.01, 0.88 ± 0.01 (HCHO > FAT-adapt, P < 0.05), 0.95 ± 0.01 (HCHO > FAT-adapt, P < 0.05)). On day 7, fat oxidation remained elevated (73 ± 4 g vs 45 ± 3 g, P < 0.05), whereas CHO oxidation was reduced (354 ± 11 g vs 419 ± 13 g, P < 0.05) throughout SS in FAT-adapt versus HCHO. TT performance was similar for both trials (25.53 ± 0.67 min vs 25.45 ± 0.96 min, NS). Conclusion: Adaptations to a short-term high-fat diet persisted in the face of high CHO availability before and during exercise, but failed to confer a performance advantage during a TT lasting ∼ 25 min undertaken after 2 h of submaximal cycling.

Original languageEnglish
Pages (from-to)83-91
Number of pages9
JournalMedicine and Science in Sports and Exercise
Volume34
Issue number1
DOIs
Publication statusPublished - 1 Jan 2002
Externally publishedYes

Fingerprint

High Fat Diet
Fats
Carbohydrates
Breakfast
Diet

Cite this

Burke, Louise M. ; Hawley, John A. ; Angus, Damien J. ; Cox, Gregory R. ; Clark, Sally A. ; Cummings, Nicola K. ; Desbrow, Ben ; Hargreaves, Mark. / Adaptations to short-term high-fat diet persist during exercise despite high carbohydrate availability. In: Medicine and Science in Sports and Exercise. 2002 ; Vol. 34, No. 1. pp. 83-91.
@article{7b978fc7144643bcab03ab7151304fc9,
title = "Adaptations to short-term high-fat diet persist during exercise despite high carbohydrate availability",
abstract = "Purpose: Five days of a high-fat diet produce metabolic adaptations that increase the rate of fat oxidation during prolonged exercise. We investigated whether enhanced rates of fat oxidation during submaximal exercise after 5 d of a high-fat diet would persist in the face of increased carbohydrate (CHO) availability before and during exercise. Methods: Eight well-trained subjects consumed either a high-CHO (9.3 g·kg-1·d-1 CHO, 1.1 g·kg-1·d-1 fat; HCHO) or an isoenergetic high-fat diet (2.5 g·kg-1·d-1 CHO, 4.3 g·kg-1·d-1 fat; FAT-adapt) for 5 d followed by a high-CHO diet and rest on day 6. On day 7, performance testing (2 h steady-state (SS) cycling at 70{\%} peak O2 uptake [V̇O2peak] + time trial [TT]) of 7 kJ·kg-1) was undertaken after a CHO breakfast (CHO 2 g·kg-1) and intake of CHO during cycling (0.8 g·kg-1·h-1). Results: FAT-adapt reduced respiratory exchange ratio (RER) values before and during cycling at 70{\%} V̇O2peak; RER was restored by I d CHO and CHO intake during cycling (0.90 ± 0.01, 0.8 ± 0.01, 0.91 ± 0.01, for days 1, 6, and 7, respectively). RER values were higher with HCHO (0.90 ± 0.01, 0.88 ± 0.01 (HCHO > FAT-adapt, P < 0.05), 0.95 ± 0.01 (HCHO > FAT-adapt, P < 0.05)). On day 7, fat oxidation remained elevated (73 ± 4 g vs 45 ± 3 g, P < 0.05), whereas CHO oxidation was reduced (354 ± 11 g vs 419 ± 13 g, P < 0.05) throughout SS in FAT-adapt versus HCHO. TT performance was similar for both trials (25.53 ± 0.67 min vs 25.45 ± 0.96 min, NS). Conclusion: Adaptations to a short-term high-fat diet persisted in the face of high CHO availability before and during exercise, but failed to confer a performance advantage during a TT lasting ∼ 25 min undertaken after 2 h of submaximal cycling.",
author = "Burke, {Louise M.} and Hawley, {John A.} and Angus, {Damien J.} and Cox, {Gregory R.} and Clark, {Sally A.} and Cummings, {Nicola K.} and Ben Desbrow and Mark Hargreaves",
year = "2002",
month = "1",
day = "1",
doi = "10.1097/00005768-200201000-00014",
language = "English",
volume = "34",
pages = "83--91",
journal = "Medicine and science in sports",
issn = "0195-9131",
publisher = "Lippincott Williams & Wilkins",
number = "1",

}

Adaptations to short-term high-fat diet persist during exercise despite high carbohydrate availability. / Burke, Louise M.; Hawley, John A.; Angus, Damien J.; Cox, Gregory R.; Clark, Sally A.; Cummings, Nicola K.; Desbrow, Ben; Hargreaves, Mark.

In: Medicine and Science in Sports and Exercise, Vol. 34, No. 1, 01.01.2002, p. 83-91.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Adaptations to short-term high-fat diet persist during exercise despite high carbohydrate availability

AU - Burke, Louise M.

AU - Hawley, John A.

AU - Angus, Damien J.

AU - Cox, Gregory R.

AU - Clark, Sally A.

AU - Cummings, Nicola K.

AU - Desbrow, Ben

AU - Hargreaves, Mark

PY - 2002/1/1

Y1 - 2002/1/1

N2 - Purpose: Five days of a high-fat diet produce metabolic adaptations that increase the rate of fat oxidation during prolonged exercise. We investigated whether enhanced rates of fat oxidation during submaximal exercise after 5 d of a high-fat diet would persist in the face of increased carbohydrate (CHO) availability before and during exercise. Methods: Eight well-trained subjects consumed either a high-CHO (9.3 g·kg-1·d-1 CHO, 1.1 g·kg-1·d-1 fat; HCHO) or an isoenergetic high-fat diet (2.5 g·kg-1·d-1 CHO, 4.3 g·kg-1·d-1 fat; FAT-adapt) for 5 d followed by a high-CHO diet and rest on day 6. On day 7, performance testing (2 h steady-state (SS) cycling at 70% peak O2 uptake [V̇O2peak] + time trial [TT]) of 7 kJ·kg-1) was undertaken after a CHO breakfast (CHO 2 g·kg-1) and intake of CHO during cycling (0.8 g·kg-1·h-1). Results: FAT-adapt reduced respiratory exchange ratio (RER) values before and during cycling at 70% V̇O2peak; RER was restored by I d CHO and CHO intake during cycling (0.90 ± 0.01, 0.8 ± 0.01, 0.91 ± 0.01, for days 1, 6, and 7, respectively). RER values were higher with HCHO (0.90 ± 0.01, 0.88 ± 0.01 (HCHO > FAT-adapt, P < 0.05), 0.95 ± 0.01 (HCHO > FAT-adapt, P < 0.05)). On day 7, fat oxidation remained elevated (73 ± 4 g vs 45 ± 3 g, P < 0.05), whereas CHO oxidation was reduced (354 ± 11 g vs 419 ± 13 g, P < 0.05) throughout SS in FAT-adapt versus HCHO. TT performance was similar for both trials (25.53 ± 0.67 min vs 25.45 ± 0.96 min, NS). Conclusion: Adaptations to a short-term high-fat diet persisted in the face of high CHO availability before and during exercise, but failed to confer a performance advantage during a TT lasting ∼ 25 min undertaken after 2 h of submaximal cycling.

AB - Purpose: Five days of a high-fat diet produce metabolic adaptations that increase the rate of fat oxidation during prolonged exercise. We investigated whether enhanced rates of fat oxidation during submaximal exercise after 5 d of a high-fat diet would persist in the face of increased carbohydrate (CHO) availability before and during exercise. Methods: Eight well-trained subjects consumed either a high-CHO (9.3 g·kg-1·d-1 CHO, 1.1 g·kg-1·d-1 fat; HCHO) or an isoenergetic high-fat diet (2.5 g·kg-1·d-1 CHO, 4.3 g·kg-1·d-1 fat; FAT-adapt) for 5 d followed by a high-CHO diet and rest on day 6. On day 7, performance testing (2 h steady-state (SS) cycling at 70% peak O2 uptake [V̇O2peak] + time trial [TT]) of 7 kJ·kg-1) was undertaken after a CHO breakfast (CHO 2 g·kg-1) and intake of CHO during cycling (0.8 g·kg-1·h-1). Results: FAT-adapt reduced respiratory exchange ratio (RER) values before and during cycling at 70% V̇O2peak; RER was restored by I d CHO and CHO intake during cycling (0.90 ± 0.01, 0.8 ± 0.01, 0.91 ± 0.01, for days 1, 6, and 7, respectively). RER values were higher with HCHO (0.90 ± 0.01, 0.88 ± 0.01 (HCHO > FAT-adapt, P < 0.05), 0.95 ± 0.01 (HCHO > FAT-adapt, P < 0.05)). On day 7, fat oxidation remained elevated (73 ± 4 g vs 45 ± 3 g, P < 0.05), whereas CHO oxidation was reduced (354 ± 11 g vs 419 ± 13 g, P < 0.05) throughout SS in FAT-adapt versus HCHO. TT performance was similar for both trials (25.53 ± 0.67 min vs 25.45 ± 0.96 min, NS). Conclusion: Adaptations to a short-term high-fat diet persisted in the face of high CHO availability before and during exercise, but failed to confer a performance advantage during a TT lasting ∼ 25 min undertaken after 2 h of submaximal cycling.

UR - http://www.scopus.com/inward/record.url?scp=0036144248&partnerID=8YFLogxK

U2 - 10.1097/00005768-200201000-00014

DO - 10.1097/00005768-200201000-00014

M3 - Article

VL - 34

SP - 83

EP - 91

JO - Medicine and science in sports

JF - Medicine and science in sports

SN - 0195-9131

IS - 1

ER -