A comparison between Yfiler® and RM Y-STRs in United Arab Emirates population

R. Alghafri*, S. Alhammadi, K. Amiri

*Corresponding author for this work

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Rapidly Mutating Y-STRs (RM Y-STR) were proven to have significantly higher resolution in worldwide populations when compared to commonly used Y-STR kits. In order to contribute to the research that has been conducted so far, RM Y-STRs were investigated in parallel with Yfiler® kit in 327 male individuals from United Arab Emirates population. Such population is considerably isolated where Yfiler® and Powerplex® Y haplotypes were found to be shared between distantly related as well as non-related male individuals. In the present study, a comparison between Y-STR markers included in Yfiler® kit (DYS456, DYS389I, DYS390, DYS389II, DYS458, DYS19, DYS385, DYS393, DYS391, DYS439, DYS635, DYS392, YGATAH4, DYS437, DYS438, DYS448) with RM Y-STRs (DYF387S1, DYF399S1, DYF403S1a/b, DYF404S1, DYS449, DYS518, DYS526a/b, DYS547, DYS570, DYS576, DYS612, DYS626, and DYS627) is conducted. RM Y-STRs were analysed using previously published methods. Forensic parameters were calculated for each set of markers, including discrimination capacity, haplotype diversity and gene diversity, using Arlequin v3.5 software.

Original languageEnglish
Pages (from-to)e650-e652
JournalForensic Science International: Genetics Supplement Series
Volume5
DOIs
Publication statusPublished - 1 Dec 2015
Externally publishedYes

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United Arab Emirates
Haplotypes
Population
Software
Research
Genes

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title = "A comparison between Yfiler{\circledR} and RM Y-STRs in United Arab Emirates population",
abstract = "Rapidly Mutating Y-STRs (RM Y-STR) were proven to have significantly higher resolution in worldwide populations when compared to commonly used Y-STR kits. In order to contribute to the research that has been conducted so far, RM Y-STRs were investigated in parallel with Yfiler{\circledR} kit in 327 male individuals from United Arab Emirates population. Such population is considerably isolated where Yfiler{\circledR} and Powerplex{\circledR} Y haplotypes were found to be shared between distantly related as well as non-related male individuals. In the present study, a comparison between Y-STR markers included in Yfiler{\circledR} kit (DYS456, DYS389I, DYS390, DYS389II, DYS458, DYS19, DYS385, DYS393, DYS391, DYS439, DYS635, DYS392, YGATAH4, DYS437, DYS438, DYS448) with RM Y-STRs (DYF387S1, DYF399S1, DYF403S1a/b, DYF404S1, DYS449, DYS518, DYS526a/b, DYS547, DYS570, DYS576, DYS612, DYS626, and DYS627) is conducted. RM Y-STRs were analysed using previously published methods. Forensic parameters were calculated for each set of markers, including discrimination capacity, haplotype diversity and gene diversity, using Arlequin v3.5 software.",
author = "R. Alghafri and S. Alhammadi and K. Amiri",
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A comparison between Yfiler® and RM Y-STRs in United Arab Emirates population. / Alghafri, R.; Alhammadi, S.; Amiri, K.

In: Forensic Science International: Genetics Supplement Series, Vol. 5, 01.12.2015, p. e650-e652.

Research output: Contribution to journalArticleResearchpeer-review

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