Abstract
Interstitial cystitis/bladder pain syndrome (IC/BPS) remains a clinical enigma. Estimated to affect over 8 million women globally, it is a challenge to diagnose and to treat effectively, due to an unknown etiology and complex, poorly understood pathophysiology. Clinical diagnosis is symptom-based, with patients experiencing debilitating chronic pelvic or bladder pain, pressure or discomfort, along with urinary storage symptoms including frequency and urgency. IC/BPS is also associated with depression and anxiety.
| Original language | English |
|---|---|
| Journal | American Journal of Physiology - Renal Physiology |
| DOIs | |
| Publication status | E-pub ahead of print - 27 Jun 2018 |
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A central role for toll-like 4 (TLR4) receptors in interstitial cystitis? / Sellers, Donna Jayne; McDermott, Catherine; Chess-Williams, Russ.
In: American Journal of Physiology - Renal Physiology, 27.06.2018.Research output: Contribution to journal › Article › Research › peer-review
TY - JOUR
T1 - A central role for toll-like 4 (TLR4) receptors in interstitial cystitis?
AU - Sellers, Donna Jayne
AU - McDermott, Catherine
AU - Chess-Williams, Russ
PY - 2018/6/27
Y1 - 2018/6/27
N2 - [Extract] Interstitial cystitis/bladder pain syndrome (IC/BPS) remains a clinical enigma. Estimated to affect over 8 million women globally, it is a challenge to diagnose and to treat effectively, due to an unknown etiology and complex, poorly understood pathophysiology. Clinical diagnosis is symptom-based, with patients experiencing debilitating chronic pelvic or bladder pain, pressure or discomfort, along with urinary storage symptoms including frequency and urgency. IC/BPS is also associated with depression and anxiety.
AB - [Extract] Interstitial cystitis/bladder pain syndrome (IC/BPS) remains a clinical enigma. Estimated to affect over 8 million women globally, it is a challenge to diagnose and to treat effectively, due to an unknown etiology and complex, poorly understood pathophysiology. Clinical diagnosis is symptom-based, with patients experiencing debilitating chronic pelvic or bladder pain, pressure or discomfort, along with urinary storage symptoms including frequency and urgency. IC/BPS is also associated with depression and anxiety.
U2 - 10.1152/ajprenal.00290.2018
DO - 10.1152/ajprenal.00290.2018
M3 - Article
JO - American Journal of Physiology - Renal Physiology
JF - American Journal of Physiology - Renal Physiology
SN - 1522-1466
ER -