Abstract
Interstitial cystitis/bladder pain syndrome (IC/BPS) remains a clinical enigma. Estimated to affect over 8 million women globally, it is a challenge to diagnose and to treat effectively, due to an unknown etiology and complex, poorly understood pathophysiology. Clinical diagnosis is symptom-based, with patients experiencing debilitating chronic pelvic or bladder pain, pressure or discomfort, along with urinary storage symptoms including frequency and urgency. IC/BPS is also associated with depression and anxiety.
| Original language | English |
|---|---|
| Pages (from-to) | F910-F912 |
| Journal | American Journal of Physiology - Renal Physiology |
| Volume | 315 |
| Issue number | 4 |
| Early online date | 27 Jun 2018 |
| DOIs | |
| Publication status | Published - 1 Oct 2018 |
Fingerprint
Cite this
}
A central role for Toll-like 4 receptors in interstitial cystitis? / Sellers, Donna Jayne; McDermott, Catherine; Chess-Williams, Russ.
In: American Journal of Physiology - Renal Physiology, Vol. 315, No. 4, 01.10.2018, p. F910-F912.Research output: Contribution to journal › Article › Research › peer-review
TY - JOUR
T1 - A central role for Toll-like 4 receptors in interstitial cystitis?
AU - Sellers, Donna Jayne
AU - McDermott, Catherine
AU - Chess-Williams, Russ
PY - 2018/10/1
Y1 - 2018/10/1
N2 - [Extract] Interstitial cystitis/bladder pain syndrome (IC/BPS) remains a clinical enigma. Estimated to affect over 8 million women globally, it is a challenge to diagnose and to treat effectively, due to an unknown etiology and complex, poorly understood pathophysiology. Clinical diagnosis is symptom-based, with patients experiencing debilitating chronic pelvic or bladder pain, pressure or discomfort, along with urinary storage symptoms including frequency and urgency. IC/BPS is also associated with depression and anxiety.
AB - [Extract] Interstitial cystitis/bladder pain syndrome (IC/BPS) remains a clinical enigma. Estimated to affect over 8 million women globally, it is a challenge to diagnose and to treat effectively, due to an unknown etiology and complex, poorly understood pathophysiology. Clinical diagnosis is symptom-based, with patients experiencing debilitating chronic pelvic or bladder pain, pressure or discomfort, along with urinary storage symptoms including frequency and urgency. IC/BPS is also associated with depression and anxiety.
UR - http://www.scopus.com/inward/record.url?scp=85071624118&partnerID=8YFLogxK
U2 - 10.1152/ajprenal.00290.2018
DO - 10.1152/ajprenal.00290.2018
M3 - Article
VL - 315
SP - F910-F912
JO - American Journal of Physiology - Renal Physiology
JF - American Journal of Physiology - Renal Physiology
SN - 1522-1466
IS - 4
ER -