The accuracy of the GLIM criteria to Assess nutritional status in inpatients with cancer and Predict nutritional status and quality of life changes during and post hospital discharge – the MAP-study

  • Van der Meij, Barbara (Project Lead)
  • Hughes, Elyssa (Partner Investigator)
  • de Groot, Lynette (Partner Investigator)
  • Jobber, Chloe (Partner Investigator)
  • Ieng Ao, Cheng (Partner Investigator)
  • Wong, Joanna (Partner Investigator)
  • Varadkar, Shifra (Partner Investigator)

Project: Research

Description

This is a prospective observational cohort study aimed to answer the following questions:
(1) Are the GLIM diagnostic criteria accurate for diagnosing malnutrition compared to the PG-SGA in cancer patients?
(2) Are GLIM criteria and PG-SGA able to predict changes in nutritional status and quality of life during admission and one month post discharge?
To address the research questions, this study compares the Global Leadership Initiative on Malnutrition (GLIM) criteria for the diagnosis of malnutrition against the gold standard malnutrition assessment tool the Patient-Generated Subjective Global Assessment (PG-SGA). The study will demonstrate the level of agreement of the GLIM criteria which includes objective phenotypic assessments of muscle mass and muscle strength using bioelectrical-impendence spectroscopy (BIS), and handgrip strength, against the gold standard tool (PG-SGA). Reduced muscle mass is a phenotypic criteria with strong evidence to support its inclusion in the GLIM criteria, however there no consensus regarding how best to measure and define reduced muscle mass. In our study we are going to measure using validated instruments for muscle mass using BIA, and muscle strength using handgrip strength test. Moreover, the study will measure patient’s quality of life and nutrition status on admission, biweekly follow-up and 1-month after discharge from hospital to identify whether these nutrition assessment tools can predict patient’s quality of life over time.

Project Aims

1. Are the GLIM diagnostic criteria for malnutrition accurate for diagnosing malnutrition compared to the PG-SGA in cancer patients?
2. Are the GLIM diagnostic criteria more accurate in predicting changes in patients’ nutritional status and quality of life during admission and 1 month after discharge than the PG-SGA?

Key findings

Accracy of GLIM critter for diagnosing malnutrition, changes over time (during admission and at 1 month post discharge)
Short titleDiagnosing malnutrition in cancer patients with GLIM
AcronymMAP-study
StatusActive
Effective start/end date2/09/1930/04/20