Design, Synthesis and Evaluation of Selective ARTD8 Inhibitors

Project: HDR Student Project

Description

Investigating the design of selective ARTD8 inhibitors towards the treatment of castration resistant prostate cancer. Taking on an in silico approach to compound design, before organic synthesis & in vitro evaluation by enzymatic assays.

Plain Language description

Using organic chemistry, this project seeks to design inhibitors that would selectively target the enzyme ARTD8, which has the potential to assist in the treatment of metastatic prostate cancer.

Project Aims

Design a selective inhibitor of ARTD8
Short titleARTD8 Inhibitors
StatusActive
Effective start/end date13/01/1913/01/23