Russ Chess-Williams

Prof

  • Bond University, Faculty of Health Sciences and Medicine

    4229 Gold Coast

    Australia

  • 7429 Citations
  • 32 h-Index
1988 …2019
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Personal profile

Research interests

Laboratory studies to enhance our knowledge of the lower urinary tract, with the aim of developing new treatments, or enhancing current treatments of the following conditions:

  • Overactive bladder
  • Cancers of the lower urinary tract
  • Stress incontinence
  • Ureteral stones
  • Benign prostatic hyperplasia
  • Erectile dysfunction

Statement for HDR students

The research group specialises in studies of the lower urinary tract using isolated tissues to examine contraction, biochemical assays to measure release of ATP, acetylcholine and prostaglandins, histological techniques to examine structure and protein distribution, molecular biology techniques to measure proteins and radioligand binding to measure receptor densities and characteristics.

Current projects examine the receptors and ion channels of the bladder, urethra, ureter, prostate and cavernosum to identify new targets for drugs to treat overactive bladder, stress incontinence, renal stones, and enlarged prostate and erectile dysfunction.

Recent studies also include the effects of cytotoxic drugs and metabolites on bladder function to identify the causes of side effects, interactions between anti-cancer drugs, and treatments to enhance the effects of radiotherapy and other cytotoxic drugs.

 

Education/Academic qualification

Pharmacology, PhD, University of Wales

External positions

University of Sheffield

1990Mar 2006

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Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1988 2019

53 Downloads (Pure)

Differential mechanisms of action of the trace amines octopamine, synephrine and tyramine on the porcine coronary and mesenteric artery

Koh, A., Chess-Williams, R. & Lohning, A. E., 29 Jul 2019, In : Scientific Reports. 9, 9 p., 10925.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
mesenteric arteries
octopamine
tyramine
coronary vessels
amines

Elevated release of inflammatory but not sensory mediators from the urothelium is maintained following epirubicin treatment

Kang, S. H., Chess-Williams, R. & McDermott, C., 15 Nov 2019, In : European Journal of Pharmacology. 863, 9 p., 172703.

Research output: Contribution to journalArticleResearchpeer-review

Urothelium
Epirubicin
Cytokines
Acetylcholine
Interleukin-8
50 Downloads (Pure)

Histamine modulation of urinary bladder urothelium, lamina propria and detrusor contractile activity via H1 and H2 receptors

Stromberga, Z., Chess-Williams, R. & Moro, C., 7 Mar 2019, In : Scientific Reports. 9, 1, 7 p., 3899.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Urothelium
Histamine H1 Receptors
Histamine H2 Receptors
Histamine
Mucous Membrane
Acrolein
Cyclophosphamide
Toxicity
Acetylcysteine
Urinary Bladder
4 Downloads (Pure)

Purinergic receptor mediated calcium signalling in urothelial cells

Chess-Williams, R., Sellers, D. J., Brierley, S. M., Grundy, D. & Grundy, L., 6 Nov 2019, In : Scientific Reports. 9, 1, 16101.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Purinergic Receptors
Calcium Signaling
Adenosine Triphosphate
Calcium
Urinary Bladder

Activities 2018 2018

  • 1 Oral presentation

Speed Research Presentations

Elisabeth Isenring (Speaker), Jaimon T Kelly (Speaker), Christian Moro (Speaker), Mark Morgan (Speaker), Anna V. Lorimer (Speaker), Vernon G Coffey (Speaker), Rae Louise Thomas (Speaker), Alexandra Bannach-Brown (Speaker), Ray N Moynihan (Speaker), Daniel Maupin (Speaker), Rob Marc Orr (Speaker), Nigel L Barnett (Speaker), Russ Chess-Williams (Speaker)
21 Nov 2018

Activity: Talk or presentationOral presentation

Press / Media

Bond establishes new Centre for Urology Research

Russ Chess-Williams

29/07/15

1 item of media coverage

Press/Media: Expert Comment

Uni lifts research

Helen O'Neill & Russ Chess-Williams

15/07/15

1 item of media coverage

Press/Media: Expert Comment

Bond expands medical research centre

Helen O'Neill & Russ Chess-Williams

14/07/15

2 items of media coverage

Press/Media: Expert Comment

Student theses

Amphetamine-like compounds in pre-workout supplements

Author: Koh, A., 10 Jun 2017

Supervisor: Lohning, A. E. (Supervisor) & Chess-Williams, R. G. (Supervisor)

Student thesis: Master's Thesis

File

Contractile activity of the bladder urothelium and lamina propria

Author: Moro, C., 9 Feb 2013

Supervisor: Chess-Williams, R. (Supervisor) & Sellers, D. J. (Supervisor)

Student thesis: Doctoral Thesis

File

Cyclophosphamide and ifosfamide: mechanisms of cytotoxic action and consequences for normal bladder function

Author: Mills, K., 10 Oct 2015

Supervisor: Chess-Williams, R. G. (Supervisor) & McDermott, C. (Supervisor)

Student thesis: Doctoral Thesis

File

Cytotoxic Drugs and their Effects on Bladder Function

Author: Kang, S. H., 10 Oct 2015

Supervisor: McDermott, C. (Supervisor) & Chess-Williams, R. G. (Supervisor)

Student thesis: Doctoral Thesis

File

Drug targets for urinary and faecal incontinence and anal fissure

Author: Folasire, O., 11 Feb 2017

Supervisor: Sellers, D. J. (Supervisor) & Chess-Williams, R. G. (Supervisor)

Student thesis: Doctoral Thesis

File