Research Output per year
Personal profile
Research interests
Laboratory studies to enhance our knowledge of the lower urinary tract, with the aim of developing new treatments, or enhancing current treatments of the following conditions:
- Overactive bladder
- Cancers of the lower urinary tract
- Stress incontinence
- Ureteral stones
- Benign prostatic hyperplasia
- Erectile dysfunction
Statement for HDR students
The research group specialises in studies of the lower urinary tract using isolated tissues to examine contraction, biochemical assays to measure release of ATP, acetylcholine and prostaglandins, histological techniques to examine structure and protein distribution, molecular biology techniques to measure proteins and radioligand binding to measure receptor densities and characteristics.
Current projects examine the receptors and ion channels of the bladder, urethra, ureter, prostate and cavernosum to identify new targets for drugs to treat overactive bladder, stress incontinence, renal stones, and enlarged prostate and erectile dysfunction.
Recent studies also include the effects of cytotoxic drugs and metabolites on bladder function to identify the causes of side effects, interactions between anti-cancer drugs, and treatments to enhance the effects of radiotherapy and other cytotoxic drugs.
Education/Academic qualification
Pharmacology, PhD, University of Wales
Award Date: 29 Jan 1984
External positions
University of Sheffield
1990 → Mar 2006Fingerprint Dive into the research topics where Russ Chess-Williams is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Network
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Research Output
Alterations in histamine responses between juvenile and adult urinary bladder urothelium, lamina propria and detrusor tissues
Stromberga, Z., Chess-Williams, R. & Moro, C., 5 Mar 2020, In : Scientific Reports. 10, 1, 9 p., 4116.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
2
Citations
(Scopus)
30
Downloads
(Pure)
A Pilot retrospective analysis of alpha-blockers on recurrence in men with localised prostate cancer treated with radiotherapy
Hart, J., Spencer, B., McDermott, C., Chess-Williams, R., Sellers, D. J., Christie, D. & Anoopkumar-Dukie, S., 18 May 2020, In : Scientific Reports. 10, 1, 7 p., 8191.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
A porcine model of ureteral contractile activity: Influences of age, tissue orientation, region, urothelium, COX and NO
Lim, I., Chess-Williams, R. & Sellers, D., 1 Mar 2020, In : Journal of Pharmacological and Toxicological Methods. 102, 8 p., 106661.Research output: Contribution to journal › Article › Research › peer-review
Hypersensitivity of bladder low threshold, wide dynamic range, afferent fibres following treatment with the chemotherapeutic drugs cyclophosphamide and ifosfamide
Mills, K., West, E., Grundy, L., McDermott, C., Sellers, D. J., Rose’Meyer, R. & Chess-Williams, R., 1 Aug 2020, In : Archives of Toxicology. 94, 8, p. 2785-2797 13 p.Research output: Contribution to journal › Article › Research › peer-review
Prostaglandin E2 and F2alpha Modulate Urinary Bladder Urothelium, Lamina Propria and Detrusor Contractility via the FP Receptor
Stromberga, Z., Chess-Williams, R. & Moro, C., 23 Jun 2020, In : Frontiers in Physiology. 11, 11 p., 705.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Activities
- 1 Oral presentation
Speed Research Presentations
Elisabeth Isenring (Speaker), Jaimon T Kelly (Speaker), Christian Moro (Speaker), Mark Morgan (Speaker), Anna V. Lorimer (Speaker), Vernon G Coffey (Speaker), Rae Louise Thomas (Speaker), Alexandra Bannach-Brown (Speaker), Ray N Moynihan (Speaker), Daniel Maupin (Speaker), Rob Marc Orr (Speaker), Nigel L Barnett (Speaker) & Russ Chess-Williams (Speaker)
21 Nov 2018
Activity: Talk or presentation › Oral presentation
Press / Media
Bond establishes new Centre for Urology Research
29/07/15
1 item of Media coverage
Press/Media: Expert Comment