Photo of Lotti Tajouri
  • Bond University, Faculty of Health Sciences and Medicine

    4229 Gold Coast

    Australia

  • 1314 Citations
  • 17 h-Index
20032020

Research output per year

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Research Output

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Article
2020

Erythrocyte microRNAs show biomarker potential and implicate multiple sclerosis susceptibility genes

Groen, K., Maltby, V. E., Scott, R. J., Tajouri, L. & Lechner-Scott, J., 10 Apr 2020, In : Clinical and Translational Medicine. 10, 1, p. 74-90 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2019

Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility

International Multiple Sclerosis Genetics Consortium, 27 Sep 2019, In : Science. 365, 6460, 12 p., 7188.

Research output: Contribution to journalArticleResearchpeer-review

The Role of Genetic Profile in Functional Performance Adaptations to Exercise Training or Physical Activity: A Systematic Review of the Literature

Wilson, G. C., Mavros, Y., Tajouri, L. & Singh, M. F., 24 Jan 2019, In : Journal of Aging and Physical Activity. 27, 4, p. 594-616 23 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)
2018

Erythrocyte microRNA sequencing reveals differential expression in relapsing-remitting multiple sclerosis

Groen, K., Maltby, V. E., Lea, R. A., Sanders, K. A., Fink, J. L., Scott, R. J., Tajouri, L. & Lechner-Scott, J., 21 May 2018, In : BMC Medical Genomics. 11, 1, 12 p., 48.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
5 Citations (Scopus)
123 Downloads (Pure)

Genome-wide DNA methylation changes in CD19+ B cells from relapsing-remitting multiple sclerosis patients

Maltby, V. E., Lea, R. A., Graves, M. C., Sanders, K. A., Benton, M. C., Tajouri, L., Scott, R. J. & Lechner-Scott, J., 27 Nov 2018, In : Scientific Reports. 8, 1, 10 p., 17418.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
5 Citations (Scopus)
130 Downloads (Pure)

Low-Frequency and Rare-Coding Variation Contributes to Multiple Sclerosis Risk

International Multiple Sclerosis Genetics Consortium, 29 Nov 2018, In : Cell. 175, 6, p. 1679-1687.e7

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
29 Citations (Scopus)
133 Downloads (Pure)
2017

Response to interferon-beta treatment in multiple sclerosis patients: A genome-wide association study

ANZgene Consortium & Tajouri, L., 1 Jul 2017, In : Pharmacogenomics Journal. 17, 4, p. 312-318 7 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)
2016
Open Access
File
10 Citations (Scopus)
135 Downloads (Pure)

Decrease of DHEA-S concentration succeeding a micro-dose thumb exertion: Mood-state determinants reflect stress-biomarker responses

Szlezak, A. M., Tajouri, L., Szlezak, S. L., Keane, J. & Minahan, C., 1 Dec 2016, In : SpringerPlus. 5, 1, 1446.

Research output: Contribution to journalArticleResearchpeer-review

Erythrocytes in multiple sclerosis: forgotten contributors to the pathophysiology?

Groen, K., Maltby, V. E., Sanders, K., Scott, R. J., Tajouri, L. & Lechner-Scott, J., 2016, In : Multiple Sclerosis. 2, p. 1-9 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
158 Downloads (Pure)

Genetic loci for Epstein-Barr virus nuclear antigen-1 are associated with risk of multiple sclerosis

ANZgene Consortium & Tajouri, L., 1 Nov 2016, In : Multiple Sclerosis. 22, 13, p. 1655-1664 10 p.

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

Isometric thumb exertion induces B cell and T cell lymphocytosis in trained and untrained males: Physical aptitude determines response profiles

Szlezak, A. M., Tajouri, L., Keane, J., Lauluten, S. L. & Minahan, C., 2016, In : International Journal of Kinesiology and Sports Science. 4, 1, p. 55-66 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Next-generation sequencing reveals broad down-regulation of microRNAs in secondary progressive multiple sclerosis CD4+ T cells

Sanders, K. A., Benton, M. C., Lea, R. A., Maltby, V. E., Agland, S., Griffin, N., Scott, R. J., Tajouri, L. & Lechner-Scott, J., 27 Aug 2016, In : Clinical Epigenetics. 8, 1, 87.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
20 Citations (Scopus)
4 Downloads (Pure)
Open Access
File
1 Citation (Scopus)
4 Downloads (Pure)
2015

A rare P2X7 variant Arg307Gln with absent pore formation function protects against neuroinflammation in multiple sclerosis

Gu, B. J., Field, J., Dutertre, S., Ou, A., Kilpatrick, T. J., Lechner-Scott, J., Scott, R. J., Lea, R. A., Taylor, B. V., Stankovich, J., Butzkueven, H., Gresle, M., Laws, S. M., Petrou, S., Hoffjan, S., Akkad, D. A., Graham, C. A., Hawkins, S., Glaser, A., Bedri, S. K. & 25 others, Hillert, J., Matute, C., Antiguedad, A., ANZgene Consortium, Baxter, A. G., Kermode, A. G., Taylor, B., Booth, D. R., Mason, D. F., Stewart, G. J., Butzkueven, H., Charlesworth, J. C., Wiley, J., Tajouri, L., Griffiths, L. R., Slee, M., Brown, M. A., Moscato, P., Scott, R. J., Broadley, S. A., Vucic, S., Kilpatrick, T. J., Carrol, W. M., Barnett, M. H. & Wiley, J. S., 1 Oct 2015, In : Human Molecular Genetics. 24, 19, p. 5644-5654 11 p., ddv278.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
28 Citations (Scopus)

Genome-wide DNA methylation profiling of CD8+ T cells shows a distinct epigenetic signature to CD4+ T cells in multiple sclerosis patients

Maltby, V. E., Graves, M. C., Lea, R. A., Benton, M. C., Sanders, K. A., Tajouri, L., Scott, R. J. & Lechner-Scott, J., 5 Nov 2015, In : Clinical Epigenetics. 7, 1, 118.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
39 Citations (Scopus)
5 Downloads (Pure)

Micro-dose of resistance-exercise: Effects of sub-maximal thumb exertion on leukocyte redistribution and fatigue in trained male weightlifters

Szlezak, A. M., Tajouri, L., Keane, J., Szlezak, S. L. & Minahan, C., 28 Sep 2015, In : Journal of Physical Education and Sport. 15, 3, p. 365-377 13 p., 55.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
4 Citations (Scopus)

The effect of growth hormone administration on the regulation of mitochondrial apoptosis in-vivo

Keane, J., Tajouri, L. & Gray, B., 5 Jun 2015, In : International Journal of Molecular Sciences. 16, 6, p. 12753-12772 20 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
8 Citations (Scopus)
4 Downloads (Pure)

The MS risk allele of CD40 is associated with reduced cell-membrane bound expression in antigen presenting cells: Implications for gene function

Field, J., Shahijanian, F., Schibeci, S., Australia and New Zealand MS Genetics Consortium, Baxter, A., Kermode, A. G., Taylor, B., Booth, D. R., Mason, D., Stewart, G. J., Butzkueven, H., Charlesworth, J., Wiley, J., Lechner-Scott, J., Field, J., Tajouri, L., Griffiths, L. R., Slee, M., Brown, M. A., Moscato, P. & 14 others, Scott, R. J., Broadley, S., Vucic, S., Kilpatrick, T., Carroll, W. M., Johnson, L., Gresle, M., Laverick, L., Parnell, G., Stewart, G., McKay, F., Kilpatrick, T., Butzkueven, H. & Booth, D. R., 11 Jun 2015, In : PLoS One. 10, 6, e0127080.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
21 Citations (Scopus)
4 Downloads (Pure)
2014

Methylation differences at the HLA-DRB1 locus in CD4+ T-Cells are associated with multiple sclerosis

Graves, M. C., Benton, M. C., Lea, R. A., Boyle, F. M., Tajouri, L., Macartney-Coxson, D., Scott, R. J. & Lechner-Scott, J., 2014, In : Multiple Sclerosis. 20, 8, p. 1033-1041 9 p.

Research output: Contribution to journalArticleResearchpeer-review

68 Citations (Scopus)

The CYP27B1 variant associated with an increased risk of autoimmune disease is underexpressed in tolerizing dendritic cells

ANZgene Multiple Sclerosis Genetics Consortium, 24 Oct 2014, In : Human Molecular Genetics. 23, 6, p. 1425-1434 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
23 Citations (Scopus)
4 Citations (Scopus)
2013

Adrenoceptor function and expression in bladder urothelium and lamina propria

Moro, C., Tajouri, L. & Chess-Williams, R., Jan 2013, In : Urology. 81, 1

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

Heat shock proteins and regulatory T cells

Brenu, E. W., Staines, D. R., Tajouri, L., Huth, T., Ashton, K. J. & Marshall-Gradisnik, S. M., 2013, In : Autoimmune Diseases. 2013, 8 p., 813256.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
11 Citations (Scopus)
8 Downloads (Pure)

Identity-by-Descent Mapping to Detect Rare Variants Conferring Susceptibility to Multiple Sclerosis

ANZgene Consortium, 5 Mar 2013, In : PLoS One. 8, 3, e56379.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
13 Citations (Scopus)

Resequencing and fine-mapping of the chromosome 12q13-14 locus associated with multiple sclerosis refines the number of implicated genes

Cortes, A., Field, J., Glazov, E. A., Hadler, J., Stankovich, J., Brown, M. A., Baxter, A., Kermode, A. G., Taylor, B., Booth, D. R., Mason, D., Stewart, G. J., Butzkueven, H., Charlesworth, J., Wiley, J., Lechner-Scott, J., Field, J., Tajouri, L., Griffiths, L. R., Slee, M. & 7 others, Brown, M. A., Moscato, P., Scott, R. J., Broadley, S., Vucic, S., Kilpatrick, T. J. & Carroll, W. M., Jun 2013, In : Human Molecular Genetics. 22, 11, p. 2283-2292 10 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)
2012

Closing the case of APOE in multiple sclerosis: No association with disease risk in over 29 000 subjects

Australia and New Zealand Multiple Sclerosis Genetics Consortium (ANZgene), 1 Sep 2012, In : Journal of Medical Genetics. 49, 9, p. 558-562 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Interleukin-6 gene promoter-572 C allele may play a role in rate of disease progression in multiple sclerosis

Australia and New Zealand Multiple Sclerosis Genetics Consortium (ANZgene) & Tajouri, L., 1 Oct 2012, In : International Journal of Molecular Sciences. 13, 10, p. 13667-13679 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
14 Citations (Scopus)

Longitudinal investigation of natural killer cells and cytokines in chronic fatigue syndrome/myalgic encephalomyelitis

Brenu, E. W., van Driel, M. L., Staines, D. R., Ashton, K. J., Hardcastle, S. L., Keane, J., Tajouri, L., Peterson, D., Ramos, S. B. & Marshall-Gradisnik, S. M., 2012, In : Journal of Translational Medicine. 10, p. 88

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
84 Citations (Scopus)
6 Downloads (Pure)
2011

Assessment of immune function after short-term administration of recombinant human growth hormone in healthy young males

Ramos, S. B., Brenu, E. W., Christy, R., Gray, B., McNaughton, L., Tajouri, L., Van Driel, M. & Marshall-Gradisnik, S. M., Jul 2011, In : European Journal of Applied Physiology. 111, 7, p. 1307-1312 6 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Comparing genotyping algorithms for Illumina's Infinium whole-genome SNP BeadChips

Ritchie, M. E., Liu, R., Carvalho, B. S., Irizarry, R. A., Bahlo, M., Booth, D. R., Broadley, S. A., Brown, M. A., Foote, S. J., Griffiths, L. R., Kilpatrick, T. J., Lechner-Scott, J., Moscato, P., Perreau, V. M., Rubio, J. P., Scott, R. J., Stankovich, J., Stewart, G. J., Taylor, B. V., Wiley, J. & 50 others, Brown, M. A., Booth, D. R., Clarke, G., Cox, M. B., Csurhes, P. A., Danoy, P., Dickinson, J. L., Drysdale, K., Field, J., Foote, S. J., Greer, J. M., Guru, P., Hadler, J., Hoban, E., McMorran, B. J., Jensen, C. J., Johnson, L. J., McCallum, R., Merriman, M., Merriman, T., Polanowski, A., Pryce, K., Scott, R. J., Stewart, G. J., Tajouri, L., Whittock, L., Wilkins, E. J., Rubio, J. P., Bahlo, M., Brown, M. A., Browning, B. L., Browning, S. R., Perera, D., Rubio, J. P., Broadley, S., Broadley, S., Butzkueven, H., Carroll, W. M., Kermode, A. G., Marriott, M., Mason, D., Heard, R. N., Pender, M. P., Pender, M. P., Tubridy, N., Lechner-Scott, J., Taylor, B. V., Willoughby, E., Kilpatrick, T. J. & Kilpatrick, T. J., 8 Mar 2011, In : BMC Bioinformatics. 12, 68.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
32 Citations (Scopus)

The effects of short term recombinant human growth hormone (rhGH) on blood rheology in healthy young males

Ramos, S. B., Brun, J. F., Gray, B., Rogerson, S., Weatherby, R. P., Tajouri, L. & Marshall-Gradisnik, S. M., 2011, In : Clinical Hemorheology and Microcirculation. 47, 2, p. 121-129 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)
2010

Investigation of the [-/A]8 and C1236T genetic variations within the human Toll-like receptor 3 gene for association with multiple sclerosis

Szvetko, A. L., Jones, A., Mackenzie, J., Tajouri, L., Csurhes, P. A., Greer, J. M., Pender, M. P. & Griffiths, L. R., May 2010, In : Neurological Research. 32, 4, p. 438-41 4 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Saliva-derived DNA performs well in large-scale, high-density single-nucleotide polymorphism microarray studies

The Australian and New Zealand Multiple Sclerosis Genetics Consortium (ANZgene) & Tajouri, L., 1 Mar 2010, In : Cancer Epidemiology Biomarkers and Prevention. 19, 3, p. 794-798 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2009

An investigation of the C77G and C772T variations within the human protein tyrosine phosphatase receptor type C gene for association with multiple sclerosis in an Australian population

Szvetko, A. L., Jones, A., Mackenzie, J., Tajouri, L., Csurhes, P. A., Greer, J. M., Pender, M. P. & Griffiths, L. R., 19 Feb 2009, In : Brain Research. 1255, p. 148-152 5 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Study of leukemia inhibitory factor polymorphism within an Australian multiple sclerosis population

Mackenzie, J., Tajouri, L., Szvetko, A. L., Weth, V., Moreau, J., Greer, J. M., Csurhes, P. A., Pender, M. P. & Griffiths, L. R., 15 May 2009, In : Journal of the Neurological Sciences. 280, 1-2, p. 62-64 3 p.

Research output: Contribution to journalArticleResearchpeer-review

2007

Allelic variation investigation of the estrogen receptor within an Australian multiple sclerosis population

Tajouri, L., Fernandez, F., Tajouri, S., Detriche, G., Szvetko, A. L., Colson, N., Csurhes, P. A., Pender, M. P. & Griffiths, L. R., 15 Jan 2007, In : Journal of the Neurological Sciences. 252, 1, p. 9-12 4 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Gene expression studies in multiple sclerosis

Tajouri, L., Griffiths, L. R. & Fernandez, F., May 2007, In : Current Genomics. 8, 3, p. 181-189 9 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

No association between MTHFR A1298C and MTRR A66G polymorphisms, and MS in an Australian cohort

Szvetko, A. L., Fowdar, J., Nelson, J., Colson, N., Tajouri, L., Csurhes, P. A., Pender, M. P. & Griffiths, L. R., 15 Jan 2007, In : Journal of the Neurological Sciences. 252, 1, p. 49-52 4 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)
2006

Genetic investigation of methylenetetrahydrofolate reductase (MTHFR) and catechol-O-methyl transferase (COMT) in multiple sclerosis

Tajouri, L., Martin, J. H., Gasparini, C., Ovcaric, M., Curtain, R., Lea, R. A., Haupt, LM., Csurhes, P. A., Pender, M. P. & Griffiths, L. R., 14 Apr 2006, In : Brain Research Bulletin. 69, 3, p. 327-331 5 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

No mutations detected in the INSR gene in a chromosome 19p13 linked migraine pedigree

Curtain, R., Tajouri, L., Lea, R. A., MacMillan, J. & Griffiths, L. R., 2006, In : European Journal of Medical Genetics. 49, 1, p. 57-62 6 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)
2005

Analysis of chromosome 1 microsatellite markers and the FHM2-ATP1A2 gene mutations in migraine pedigrees

Curtain, RP., Lea, R. A., Tajouri, L., Haupt, LM., Ovcaric, M., MacMillan, J. & Griffiths, LR., Sep 2005, In : Neurological Research. 27, 6, p. 647-652 6 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

An examination of MS candidate genes identified as differentially regulated in multiple sclerosis plaque tissue, using absolute and comparative real-time Q-PCR analysis

Tajouri, L., Mellick, AS., Tourtellotte, A., Nagra, R. M. & Griffiths, L. R., Jul 2005, In : Brain Research Protocols. 15, 2, p. 79-91 13 p.

Research output: Contribution to journalArticleResearchpeer-review

23 Citations (Scopus)

Variation in the vitamin D receptor gene is associated with multiple sclerosis in an Australian population

Tajouri, L., Ovcaric, M., Curtain, R., Johnson, M. P. & Griffiths, L. R., 2005, In : Journal of Neurogenetics. 19, 1, p. 25-38 14 p.

Research output: Contribution to journalArticleResearchpeer-review

106 Citations (Scopus)
2004

Investigation of a neuronal nitric oxide synthase gene (NOS1) polymorphism in a multiple sclerosis population

Tajouri, L., Ferreira, L., Ovcaric, M., Curtain, R., Lea, R. A., Csurhes, P. A., Pender, M. P. & Griffiths, L. R., 15 Mar 2004, In : Journal of the Neurological Sciences. 218, 1-2, p. 25-28 4 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Investigation of an inducible nitric oxide synthase gene (NOS2A) polymorphism in a multiple sclerosis population

Tajouri, L., Martin, V., Ovcaric, M., Curtain, R. P., Lea, R. A., Csurhes, P. A., Pender, M. P. & Griffiths, L. R., 30 Jul 2004, In : Brain Research Bulletin. 64, 1, p. 9-13 5 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Investigation of the low-density lipoprotein receptor gene and cholesterol as a risk factor for migraine

Curtain, R., Lea, R. A., Quinlan, S., Bellis, C., Tajouri, L., Hughes, R., MacMillan, J. & Griffiths, L. R., 15 Dec 2004, In : Journal of the Neurological Sciences. 227, 1, p. 95-100 6 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

The methylentetrahydrofolate reductase gene variant (C677T) as a risk factor for essential hypertension in Caucasians

Heux, S., Morin, F., Lea, R. A., Ovcaric, M., Tajouri, L. & Griffiths, L. R., Sep 2004, In : Hypertension Research. 27, 9, p. 663-667 5 p.

Research output: Contribution to journalArticleResearchpeer-review

38 Citations (Scopus)

The role of adenosine-related genes variants in susceptibility to essential hypertension

Wright, K., Tajouri, L., Lea, R. A., Ovcaric, M., Heux, S., Morin, F., Bey, W., Headrick, J. P. & Griffiths, L. R., Aug 2004, In : Journal of Hypertension. 22, 8, p. 1519-1522 4 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)
2003

Quantitative and qualitative changes in gene expression patterns characterize the activity of plaques in multiple sclerosis

Tajouri, L., Mellick, A. S., Ashton, K. J., Tannenberg, A. E. G., Nagra, R. M., Tourtellotte, W. W. & Griffiths, L. R., 26 Nov 2003, In : Molecular Brain Research. 119, 2, p. 170-183 14 p.

Research output: Contribution to journalArticleResearchpeer-review

104 Citations (Scopus)