Personal profile
Research interests
I completed my Bachelor of Science (Physiology) and PhD at University College in Cork, Ireland, before moving to Australia in 2008.
I have conducted extensive research, with a particular focus on sub-chronic toxicity of organic solvent mixtures in vitro, and also the effects of chemotherapeutic agents on normal bladder function.
As a university lecturer/researcher, I combine a clear understanding of the teaching and learning process with in-depth subject knowledge informed by my own studies and research.
Many bladder cancer patients experience local side-effects following chemotherapy which greatly affect patient quality of life and ability to tolerate treatment. One of my main research interests is to try to understand why these side-effects occur by investigating the effects of chemotherapeutic drugs on normal bladder function. To do this we use in vitro models of the human urothelium. Through these studies we also aim to assess the ability of the urothelium to recover following treatment and determine if there are other drugs that could be used to treat bladder cancer that would be more effective and more tolerable.
Statement for HDR students
These are some of the current HDR projects and students I supervise:
- Cytotoxic drugs and their effects on bladder function - PhD student - Stanley Kang
- Cyclophosphamide and Ifosfamide: Mechanisms of urotoxicity and consequences for normal bladder function - PhD student - Kylie Mills
- Quinazoline based alpha 1-adrenoceptor antagonists and prostate cancer - PhD student - Amanda Forbes
- Interactions between urothelial mediators regulating release from cultured urothelial cells and porcine urothelial tissue - PhD student - Katrina Smith
Education/Academic qualification
PhD
Award Date: 15 Dec 2005
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
Projects
- 1 Finished
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Establishing benchmarks for diverse, person-centred simulated participant programs. ($6,500)
Stokes-Parish, J. (Chief Investigator), Gough, S. (Partner Investigator), Houghton, H. (Assistant Professor), Green, P. (Associate Investigator), Turner, C. (Associate Investigator), McDermott, C. (Associate Investigator), Alsaba, N. (Associate Investigator), Bannatyne, A. (Associate Investigator) & Marr, K. (Other)
1/05/22 → 1/09/23
Project: Research
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A feasibility study of the repurposing of prazosin to improve treatment outcomes in men receiving radiotherapy for prostate cancer (MiniRaP-00)
King, L. D., Christie, D., Cehic, D., Dare, W., Chess-Williams, R., Sellers, D., McDermott, C., McCarthy, A. & Anoopkumar-Dukie, S., Jun 2026, In: The Prostate. 86, 8, p. 891-899 9 p.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile5 Downloads (Pure) -
The Antipsychotic Aripiprazole Induces Cytotoxicity in Bladder Cancer Cells While Preserving Urothelial and Bladder Function
O'Callaghan, L. A., Powell, K., Chess‐Williams, R. & McDermott, C., 5 Jun 2026, In: Pharmacology research & perspectives. 14, 3, p. 1-12 12 p., e70260.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile12 Downloads (Pure) -
Changes in sequencing technology used for preimplantation genetic testing for aneuploidy
Oltramare, V., McDermott, C. & Dunn, P. J., Aug 2025, In: Journal of Assisted Reproduction and Genetics. 42, 8, p. 2483-2496 14 p.Research output: Contribution to journal › Review article › Research › peer-review
Open AccessFile150 Downloads (Pure) -
From Psychiatry to Oncology: Exploring the Anti‐Neoplastic Mechanisms of Aripiprazole and Its Potential Use in Cancer Treatment
O'Callaghan, L. A., Blum, C. B., Powell, K., Chess‐Williams, R. & McDermott, C., 12 Feb 2025, In: Pharmacology research & perspectives. 13, 1, p. 1-21 21 p., e70076.Research output: Contribution to journal › Review article › Research › peer-review
Open AccessFile7 Link opens in a new tab Citations (Scopus)174 Downloads (Pure) -
Identifying molecular key players in prostate cancer cell migration and metastasis
Turpie, C., Dunn, P. J., McDermott, C. & Rohl, J., 2024, p. 1-1. 1 p.Research output: Contribution to conference › Abstract › Research
Activities
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Collaborate with MIRO
McDermott, C. (Attendee)
17 Jul 2025Activity: Professional Development, Mentorship, Supervision and Other Activities › Internal Professional Development
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Using AI to Support Everyday Teaching Tasks
McDermott, C. (Attendee)
20 Jun 2025Activity: Professional Development, Mentorship, Supervision and Other Activities › Internal Professional Development
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Design Smarter, Not Harder with AI
McDermott, C. (Attendee)
19 Jun 2025Activity: Professional Development, Mentorship, Supervision and Other Activities › Internal Professional Development
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National Conference on Incontinence Pre-Conference Workshop
Sellers, D. (Speaker), Moro, C. (Speaker), Chess-Williams, R. (Facilitator) & McDermott, C. (Speaker)
19 Oct 2020 → …Activity: Participating in or organising an event › Organising a conference, workshop, ...
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9th National Symposium on Advances in Gastrointestinal & Urogenital Research
McDermott, C. (Organiser)
4 Dec 2017Activity: Participating in or organising an event › Organising a conference, workshop, ...