Projects per year
Personal profile
Research interests
I completed my Bachelor of Science (Physiology) and PhD at University College in Cork, Ireland, before moving to Australia in 2008.
I have conducted extensive research, with a particular focus on sub-chronic toxicity of organic solvent mixtures in vitro, and also the effects of chemotherapeutic agents on normal bladder function.
As a university lecturer/researcher, I combine a clear understanding of the teaching and learning process with in-depth subject knowledge informed by my own studies and research.
Many bladder cancer patients experience local side-effects following chemotherapy which greatly affect patient quality of life and ability to tolerate treatment. One of my main research interests is to try to understand why these side-effects occur by investigating the effects of chemotherapeutic drugs on normal bladder function. To do this we use in vitro models of the human urothelium. Through these studies we also aim to assess the ability of the urothelium to recover following treatment and determine if there are other drugs that could be used to treat bladder cancer that would be more effective and more tolerable.
Statement for HDR students
These are some of the current HDR projects and students I supervise:
- Cytotoxic drugs and their effects on bladder function - PhD student - Stanley Kang
- Cyclophosphamide and Ifosfamide: Mechanisms of urotoxicity and consequences for normal bladder function - PhD student - Kylie Mills
- Quinazoline based alpha 1-adrenoceptor antagonists and prostate cancer - PhD student - Amanda Forbes
- Interactions between urothelial mediators regulating release from cultured urothelial cells and porcine urothelial tissue - PhD student - Katrina Smith
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD
Award Date: 15 Dec 2005
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Collaborations and top research areas from the last five years
Projects
- 1 Finished
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Establishing benchmarks for diverse, person-centred simulated participant programs. ($6,500)
Stokes-Parish, J., Gough, S., Houghton, H., Green, P., Turner, C., McDermott, C., Alsaba, N., Bannatyne, A. & Marr, K.
1/05/22 → 1/09/23
Project: Research
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Novel inhibitors of PARP1 and PARP14: design, synthesis, and potentiation of cisplatin efficacy in cancer
Kam, C., Tauber, A. L., Zunk, M., McDermott, C., Levonis, S. M. & Schweiker, S. S., 18 Dec 2024, In: Future Medicinal Chemistry. 17, 1, p. 35-58Research output: Contribution to journal › Article › Research › peer-review
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Drivers of Radioresistance in Prostate Cancer
King, L., Bernaitis, N., Christie, D., Chess-Williams, R., Sellers, D., McDermott, C., Dare, W. & Anoopkumar-Dukie, S., 24 Sept 2022, In: Journal of Clinical Medicine. 11, 19, 5637.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile8 Citations (Scopus)102 Downloads (Pure) -
Mirabegron and solifenacin are effective for the management of the increased urinary frequency induced by psychological stress in female mice
West, E. G., McDermott, C., Chess-Williams, R. & Sellers, D. J., 20 Jul 2022, In: Scientific Reports. 12, 1, 12365.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile2 Citations (Scopus)128 Downloads (Pure) -
Partial recovery of voiding function in female mice following repeated psychological stress exposure
West, E. G., McDermott, C., Chess-Williams, R. & Sellers, D. J., 21 Apr 2022, In: PLoS One. 17, 4 April, e0266458.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile3 Citations (Scopus)97 Downloads (Pure) -
Bladder overactivity induced by psychological stress in female mice is associated with enhanced bladder contractility
West, E., Sellers, D. J., Chess-Williams, R. & McDermott, C., 15 Jan 2021, In: Life Sciences. 265, 8 p., 118735.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile20 Citations (Scopus)179 Downloads (Pure)
Activities
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9th National Symposium on Advances in Gastrointestinal & Urogenital Research
Catherine McDermott (Organiser)
4 Dec 2017Activity: Participating in or organising an event › Organising a conference, workshop, ...
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National Conference on Incontinence Pre-Conference Workshop
Donna Sellers (Speaker), Christian Moro (Speaker), Russ Chess-Williams (Facilitator) & Catherine McDermott (Speaker)
19 Oct 2020 → …Activity: Participating in or organising an event › Organising a conference, workshop, ...
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Bond University Sage Athena Swan Self-Assessment Team (External organisation)
Linda H Crane (Chair), Andrew Calder (Member), Barry Burgan (Member), Catherine McDermott (Member), Christopher Andrews (Member), Duane Kelaart (Member), Gary Brady (Member), Keitha Dunstan (Member), Kenneth Richardson (Member), Michelle Markham (Member), Tanya Forbes (Member), Donna F. Henson (Member) & Ray N Moynihan (Member)
1 Oct 2016 → 31 Mar 2019Activity: Membership › Internal memberships, committees, boards and panelists